Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTM2 | P28161 | 4/20 | 1.00 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.67 |
| ▸ | GSTP1 | P09211 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MIF | P14174 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.54 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.54 |
| ▸ | MYC | P01106 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12277671 | 1.00 | GSTM2 (1.00) | GSTM2HRH3GSTP1MEN1KMT2A | |
| SCHEMBL17788961 | 0.95 | GSTM2 (0.90) | GSTM2HRH3GSTP1MEN1KMT2A | |
| SCHEMBL8427049 | 0.89 | GSTM2 (0.81) | GSTM2HRH3GSTP1MEN1KMT2A | |
| SCHEMBL19690834 | 0.87 | GSTM2 (0.77) | GSTM2HRH3MEN1KMT2AUSP2 | |
| SCHEMBL28275153 | 0.87 | GSTM2 (0.77) | GSTM2HRH3MEN1KMT2AUSP2 | |
| SCHEMBL19400408 | 0.87 | GSTM2 (0.77) | GSTM2HRH3MEN1KMT2AUSP2 | |
| SCHEMBL4666212 | 0.87 | GSTM2 (0.77) | GSTM2HRH3MEN1KMT2AUSP2 | |
| SCHEMBL2420517 | 0.87 | GSTM2 (0.77) | GSTM2HRH3MEN1KMT2AUSP2 | |
| SCHEMBL459120 | 0.86 | GSTM2 (0.76) | GSTM2HRH3MEN1KMT2AUSP2 | |
| SCHEMBL15515612 | 0.86 | GSTM2 (0.76) | GSTM2HRH3MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796317-B2 | Use of 7-nitro-2,1,3-benzoxadiazole derivatives for anticancer therapy | Universita Degli Studi Di Roma “Tor Vergata” (IT) | 2014-08-05 | — | — | US | disclosed |
| US-20060247284-A1 | Use of 7-nitro-2,1,3 benzoxadiazole derivatives for anticancer therapy | UNIVERSITA DEGLI STUDI DI ROMA "TOR VERGATA" (IT) | 2006-11-02 | — | — | US | disclosed |
| EP-1615638-B1 | USE OF 7-NITRO-2,1,3 BENZOXADIAZOLE DERIVATIVES FOR ANTICANCER THERAPY | UNIV ROMA (IT) | 2006-09-27 | — | — | EP | disclosed |
| EP-1615638-A1 | USE OF 7-NITRO-2,1,3 BENZOXADIAZOLE DERIVATIVES FOR ANTICANCER THERAPY | Università degli Studi di Roma " Tor Vergata" (IT) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004093874-A1 | USE OF 7-NITRO-2,1,3 BENZOXADIAZOLE DERIVATIVES FOR ANTICANCER THERAPY | UNIVERSITA' DEGLI STUDI DI ROMA 'TOR VERGATA' (IT) | 2004-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247284-A1 | Use of 7-nitro-2,1,3 benzoxadiazole derivatives for anticancer therapy | GSTK1, GSTP1, GSTM1 | GSTM2 5/4885HRH3 4206/4885GSTP1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.