SCHEMBL6049359

SCHEMBL6049359

CCCCN(C)S(=O)(=O)NC(=O)c1cc(-n2c(=O)cc(C(F)(F)F)n(N)c2=O)ccc1Cl

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 3/20 0.33
SCN9A Q15858 5/20 0.33
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
CRHR1 P34998 1/20 0.30
CRHR2 Q13324 1/20 0.30
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6049387 0.95 SCN9A (0.33) P2RX7SCN9AALDH1A1LMNACRHR1
SCHEMBL6049395 0.91 SCN9A (0.34) P2RX7SCN9AALDH1A1LMNACRHR1
SCHEMBL6049451 0.91 P2RX7 (0.35) P2RX7SCN9AALDH1A1CRHR1
SCHEMBL6049436 0.88 SCN9A (0.42) SCN9A
SCHEMBL6049446 0.87 SCN9A (0.33) P2RX7SCN9ANPC1
SCHEMBL6049378 0.87 SCN9A (0.35) P2RX7SCN9AALDH1A1LMNANPC1
SCHEMBL6049400 0.86 SCN9A (0.34) SCN9A
SCHEMBL6049391 0.85 SCN9A (0.34) P2RX7SCN9AALDH1A1CRHR1CRHR2
SCHEMBL6049440 0.84 P2RX7 (0.39) P2RX7ALDH1A1LMNACRHR1CRHR2
SCHEMBL6049396 0.83 CRHR1 (0.35) P2RX7SCN9AALDH1A1LMNACRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1458237-B1 HERBICIDAL MIXTURE BASED ON 7-PYRAZOLYLBENZOXAZOLES BASF AG (DE) 2006-04-12 EP claimed
US-20050037923-A1 Herbicidal mixture based on 7-pyrazolybenzoxazoles BASF AKTIENGESELLSCHAFT (DE) 2005-02-17 US claimed
EP-1458237-B1 HERBICIDAL MIXTURE BASED ON 7-PYRAZOLYLBENZOXAZOLES BASF AG (DE) 2006-04-12 EP disclosed
US-20050037923-A1 Herbicidal mixture based on 7-pyrazolybenzoxazoles BASF AKTIENGESELLSCHAFT (DE) 2005-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050037923-A1 Herbicidal mixture based on 7-pyrazolybenzoxazoles DDT, CYP2W1, CYP3A7 P2RX7 5/4885SCN9A 3213/4885ALDH1A1 291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.