SCHEMBL6050334

SCHEMBL6050334

CCCCCCN1C(=O)c2ccccc2C1=O

nearest known ligand 0.73

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.68
CDC25A P30304 1/20 0.68
ALDH1A1 P00352 1/20 0.65
ALDH2 P05091 1/20 0.65
ALDH3A1 P30838 1/20 0.65
TDP1 Q9NUW8 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
CHRM2 P08172 2/20 0.62
MEN1 O00255 1/20 0.62
CYP1A2 P05177 1/20 0.62
CYP2C19 P33261 1/20 0.62
KMT2A Q03164 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5696592 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1
SCHEMBL9626594 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1
SCHEMBL10731237 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1
SCHEMBL732925 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1
SCHEMBL10725536 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1
SCHEMBL23731163 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1
SCHEMBL8863090 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1
SCHEMBL8862943 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1
SCHEMBL8863074 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1
SCHEMBL31406188 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5719295-A FROM N-ALKYL NITROPHTHALAMIDE GENERAL ELECTRIC COMPANY (US) 1998-02-17 US claimed
US-5688312-A INKS WITH COLORS AND IMIDES OR BISIMIDES, FOR ACOUSTIC INK PRINTER AND DROP EJECTOR XEROX CORPORATION (US) 1997-11-18 US claimed
WO-1990008137-A1 PREPARATION OF IMIDES EASTMAN KODAK COMPANY (US) 1990-07-26 WO claimed
US-4933467-A FROM CARBON MONOXIDE, AN O-DIHALO AROMATIC COMPOUND OR CIS-1,2-VINYL DIHALIDE AND PRIMARY AMINE, PALLADIUM CATALYST EASTMAN KODAK COMPANY (US) 1990-06-12 US claimed
CN-119894496-A Component systems and methods for preparing tooth whitening formulations 可碧股份有限公司 2025-04-25 CN disclosed
US-11918653-B2 Triglyceride otic formulations and uses thereof DOMPÉ FARMACEUTICI S.P.A. (IT) 2024-03-05 US disclosed
EP-4289883-A1 CURABLE RESIN COMPOSITION ADEKA CORPORATION (JP) 2023-12-13 EP disclosed
US-20210138069-A1 TRIGLYCERIDE OTIC FORMULATIONS AND USES THEREOF DOMPÉ FARMACEUTICI S.P.A. (IT) 2021-05-13 US disclosed
US-10954217-B2 Sigma receptor binders BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2021-03-23 US disclosed
US-20190177301-A1 SIGMA RECEPTOR BINDERS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2019-06-13 US disclosed
WO-2018128720-A1 URACIL CONTAINING COMPOUNDS CV6 THERAPEUTICS (NI) LIMITED (GB) 2018-07-12 WO disclosed
WO-2018098204-A1 6-MEMBERED URACIL ISOSTERES CV6 THERAPEUTICS (NI) LIMITED (GB) 2018-05-31 WO disclosed
EP-0467248-A2 Pyrazolopyridine compound and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-01-22 EP disclosed
WO-1990008137-A1 PREPARATION OF IMIDES EASTMAN KODAK COMPANY (US) 1990-07-26 WO disclosed
US-4933466-A FROM CARBON MONOXIDE, IODOBENZENE, AND ARYL PRIMARY AMIDE EASTMAN KODAK COMPANY (US) 1990-06-12 US disclosed
US-4933467-A FROM CARBON MONOXIDE, AN O-DIHALO AROMATIC COMPOUND OR CIS-1,2-VINYL DIHALIDE AND PRIMARY AMINE, PALLADIUM CATALYST EASTMAN KODAK COMPANY (US) 1990-06-12 US disclosed
US-RE32868-E Antihyperlipidemic compositions RESEARCH CORPORATION (US) 1989-02-14 US disclosed
US-4395417-A Antihyperlipidemic compositions RESEARCH CORPORATION (US) 1983-07-26 US disclosed
US-3993437-A Process for the dyeing of polyamide fibers with sulphur dyestuffs CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-11-23 US disclosed
US-3966726-A Process for the production of cyclic carboxylic acid imides AKZO N.V. (NL) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210138069-A1 TRIGLYCERIDE OTIC FORMULATIONS AND USES THEREOF CETP, LIPA, APOB CES1 324/4885CDC25A 4882/4885ALDH1A1 1354/4885
US-10954217-B2 Sigma receptor binders SIGMAR1, OPRK1, OPRL1 CES1 2183/4885CDC25A 4637/4885ALDH1A1 307/4885
US-11918653-B2 Triglyceride otic formulations and uses thereof CETP, LIPA, APOB CES1 324/4885CDC25A 4882/4885ALDH1A1 1354/4885
US-20190177301-A1 SIGMA RECEPTOR BINDERS SIGMAR1, OPRK1, OPRL1 CES1 2183/4885CDC25A 4637/4885ALDH1A1 307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.