SCHEMBL732925

SCHEMBL732925

CCCCCCCCCN1C(=O)c2ccccc2C1=O

nearest known ligand 0.73

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.68
CDC25A P30304 1/20 0.68
ALDH1A1 P00352 1/20 0.65
ALDH2 P05091 1/20 0.65
ALDH3A1 P30838 1/20 0.65
TDP1 Q9NUW8 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
CHRM2 P08172 2/20 0.62
MEN1 O00255 1/20 0.62
CYP1A2 P05177 1/20 0.62
CYP2C19 P33261 1/20 0.62
KMT2A Q03164 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5696592 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1
SCHEMBL9626594 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1
SCHEMBL10731237 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1
SCHEMBL6050334 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1
SCHEMBL10725536 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1
SCHEMBL23731163 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1
SCHEMBL8863090 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1
SCHEMBL8862943 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1
SCHEMBL8863074 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1
SCHEMBL31406188 1.00 CES1 (0.68) CES1CDC25AALDH1A1ALDH2ALDH3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1967573-B1 REFRIGERATOR OIL COMPOSITION, AND ITS USE IN REFRIGERATOR COMPRESSORS IDEMITSU KOSAN CO (JP) 2015-09-16 EP claimed
CN-101341234-B Refrigerating machine oil composition, and compressor and refrigerating apparatus for refrigerator using same IDEMITSU KOSAN CO 2012-12-05 CN claimed
US-8137577-B2 Refrigerator oil composition, and refrigerator compressor and refrigeration system using the composition IDEMITSU KOSAN CO., LTD. (JP) 2012-03-20 US claimed
CN-112105360-B BCL-2 protein degrading agent for cancer treatment 生物风险投资有限责任公司 2024-01-30 CN disclosed
WO-2023218409-A1 PHTHALIMIDE FUNGICIDE COMPOSITION ADAMA MAKHTESHIM LTD. (IL) 2023-11-16 WO disclosed
US-20230339929-A1 THERAPEUTIC AGENTS AND METHODS OF TREATMENT UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2023-10-26 US disclosed
CN-115038697-A Therapeutic agents and methods of treatment 佛罗里达大学研究基金公司 2022-09-09 CN disclosed
US-20220169628-A1 THERAPEUTIC AGENTS AND METHODS OF TREATMENT UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2022-06-02 US disclosed
EP-3920923-A2 THERAPEUTIC AGENTS AND METHODS OF TREATMENT University of Florida Research Foundation, Incorporated (US) 2021-12-15 EP disclosed
CN-113660937-A Therapeutic agents and methods of treatment 佛罗里达大学研究基金公司 2021-11-16 CN disclosed
CN-112105360-A BCL-2 protein degrading agents for cancer treatment 生物风险投资有限责任公司 2020-12-18 CN disclosed
US-20090277212-A1 REFRIGERATOR OIL COMPOSITION, AND REFRIGERATOR COMPRESSOR AND REFRIGERATION SYSTEM USING THE COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2009-11-12 US disclosed
CN-101341234-A Refrigerating machine oil composition, and compressor and refrigerating apparatus for refrigerator using same IDEMITSU KOSAN CO (JP) 2009-01-07 CN disclosed
EP-1967573-A1 REFRIGERATOR OIL COMPOSITION, AND REFRIGERATOR COMPRESSOR AND REFRIGERATION SYSTEM USING THE COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2008-09-10 EP disclosed
US-5674864-A ANALGESICS; ENDOPEPTIDASE AND ENKEPHALINASE INHIBITORS; CARDIOTONIC, PSYCHOTROPIC AND HYPERTENSIVE AGENTS ROUSSEL UCLAF (FR) 1997-10-07 US disclosed
US-5605745-A HEATING TO CURE EPOXY RESIN WITH THERMOPLASTIC PARTICLES CYTEC TECHNOLOGY CORP. (US) 1997-02-25 US disclosed
EP-0377194-B1 Toughened thermosetting structural materials CYTEC TECH CORP (US) 1995-10-18 EP disclosed
US-5242748-A Kincreasing the toughtness of a curable epoxy resin by adding a soluble or swellable thermoplastic polyimide which is fusible at resin curing temperature BASF AKTIENGESELLSCHAFT (DE) 1993-09-07 US disclosed
EP-0392348-A2 Toughened thermosetting structural materials CYTEC TECHNOLOGY CORP. (US) 1990-10-17 EP disclosed
EP-0377194-A2 Toughened thermosetting structural materials CYTEC TECHNOLOGY CORP. (US) 1990-07-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230339929-A1 THERAPEUTIC AGENTS AND METHODS OF TREATMENT SLC10A1, HDGF, NHERF1 CES1 224/4885CDC25A 252/4885ALDH1A1 430/4885
US-20220169628-A1 THERAPEUTIC AGENTS AND METHODS OF TREATMENT HDGF, NFATC1, HGF CES1 872/4885CDC25A 398/4885ALDH1A1 737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.