Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1318841 | 0.98 | HDAC1 (0.42) | HDAC1HDAC2HDAC3HDAC8FFAR3 | |
| SCHEMBL4940589 | 0.85 | HDAC1 (0.48) | HDAC1HDAC2HDAC3HDAC8FFAR3 | |
| SCHEMBL11727566 | 0.85 | CES1 (0.43) | HDAC1HDAC2HDAC3HDAC8FFAR3 | |
| SCHEMBL11556450 | 0.85 | CES1 (0.43) | HDAC1HDAC2HDAC3HDAC8FFAR3 | |
| SCHEMBL8525838 | 0.79 | LMNA (0.46) | HDAC1HDAC2HDAC3HDAC8FFAR3 | |
| SCHEMBL1930965 | 0.78 | TDP1 (0.38) | HDAC1HDAC2FFAR3CHRM1AKR1A1 | |
| SCHEMBL982455 | 0.77 | CES2 (0.50) | HDAC1HDAC2HDAC3HDAC8FFAR3 | |
| SCHEMBL4727242 | 0.74 | CA1 (0.38) | HDAC1HDAC2HDAC3HDAC8FFAR3 | |
| SCHEMBL1177027 | 0.74 | ALDH1A1 (0.41) | HDAC1HDAC2HDAC3HDAC8FFAR3 | |
| SCHEMBL3297474 | 0.74 | ALDH1A1 (0.46) | HDAC1HDAC2HDAC3HDAC8FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644435-A2 | STABILIZING COMPOSITION FOR CHLORINE-CONTAINING POLYMERS | ARKEMA (FR) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005005530-A2 | STABILIZING COMPOSITION FOR CHLORINE-CONTAINING POLYMERS | ARKEMA (FR) | 2005-01-20 | — | — | WO | disclosed |