Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2679046 | 0.77 | KDM4E (0.40) | MAPT | |
| SCHEMBL10411212 | 0.75 | — | — | |
| SCHEMBL16563088 | 0.73 | KDM4E (0.30) | MAPT | |
| SCHEMBL7754182 | 0.73 | KDM4E (0.37) | LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7670367 | 0.72 | MAPT (0.40) | LMNACYP1A2CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL5925960 | 0.72 | KDM4E (0.49) | LMNACYP1A2MAPTCYP2D6 | |
| SCHEMBL4337978 | 0.72 | LIMK1 (0.39) | — | |
| SCHEMBL3075819 | 0.69 | LMNA (0.75) | LMNAHTTCYP1A2CYP2C19MAPT | |
| SCHEMBL7463957 | 0.69 | RAB9A (0.40) | LMNACYP1A2CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL7236507 | 0.68 | NPC1 (0.41) | CYP1A2MAPTSMN1; SMN2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636232-A2 | IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | 4 AZA Bioscience nv (BE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004104005-A2 | IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | 4 AZA BIOSCIENCE NV (BE) | 2004-12-02 | — | — | WO | disclosed |