Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PKLR | P30613 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052078 | 0.95 | TDP1 (0.43) | TDP1ALDH1A1CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL6051998 | 0.89 | PDE2A (0.42) | TDP1ALDH1A1CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL6052081 | 0.83 | PDE2A (0.42) | TDP1ALDH1A1CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL6052091 | 0.77 | CDK1 (0.39) | TDP1MAPK1 | |
| SCHEMBL6051960 | 0.70 | CDK1 (0.46) | TDP1PDE2A | |
| SCHEMBL6023204 | 0.68 | PDE2A (0.51) | PDE2A | |
| SCHEMBL6023837 | 0.68 | PDE2A (0.51) | PDE2A | |
| SCHEMBL6051967 | 0.67 | CDK1 (0.42) | TDP1PDE2A | |
| SCHEMBL6023263 | 0.65 | PDE2A (0.44) | PDE2A | |
| SCHEMBL6052089 | 0.65 | PDE2A (0.49) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060229242-A1 | Composition comprising a pulmonary surfactant and a pde2 inhibitor | ALTANA PHAZMA AG (DE) | 2006-10-12 | — | — | US | claimed |