Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | XDH | P47989 | 7/20 | 0.54 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.52 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7861742 | 0.98 | ALDH1A1 (0.66) | ALDH1A1GAAKDM4EUSP2XDH | |
| SCHEMBL18034716 | 0.90 | ALDH1A1 (0.63) | ALDH1A1GAAKDM4EUSP2XDH | |
| SCHEMBL28051293 | 0.84 | KDM4E (0.57) | ALDH1A1KDM4EUSP2XDH | |
| SCHEMBL31573 | 0.83 | XDH (0.69) | XDHSLC22A12AAK1 | |
| SCHEMBL31019133 | 0.82 | XDH (0.53) | XDHSLC22A12 | |
| SCHEMBL2344031 | 0.82 | XDH (0.53) | XDHSLC22A12 | |
| SCHEMBL13182575 | 0.82 | XDH (0.53) | XDHSLC22A12 | |
| SCHEMBL17101854 | 0.81 | KDM4E (0.66) | ALDH1A1GAAKDM4EUSP2XDH | |
| SCHEMBL301279 | 0.81 | XDH (0.52) | XDHSLC22A12 | |
| SCHEMBL31571 | 0.81 | AAK1 (0.57) | XDHSLC22A12AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106674098-B | N- (3- cyano -4- alkoxyl phenyl) pyridine carboxamides and application thereof | 中国医科大学 | 2019-07-02 | — | — | CN | disclosed |
| CN-105294584-A | 1-substituted phenyl-1H-1,2,3-triazole compound as well as preparation method and application thereof | UNIV CHINA MEDICAL | 2016-02-03 | — | — | CN | disclosed |
| US-7015218-B1 | Amide compounds and medicinal use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2006-03-21 | — | — | US | disclosed |
| CN-1230421-C | Amide compound and pharmaceutical use thereof | MITSUBISHI CHEM CORP (JP) | 2005-12-07 | — | — | CN | disclosed |
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| CN-1346348-A | Amide compound and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 2002-04-24 | — | — | CN | disclosed |
| EP-1176140-A1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2002-01-30 | — | — | EP | disclosed |