Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 8/20 | 0.53 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | BLVRB | P30043 | 1/20 | 0.50 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15337448 | 0.87 | XDH (0.45) | XDHSLC22A12ABCC4ABCB11PGR | |
| SCHEMBL31573 | 0.85 | XDH (0.69) | XDHSLC22A12ABCC4ABCB11PGR | |
| SCHEMBL31019133 | 0.83 | XDH (0.53) | XDHSLC22A12ABCC4ABCB11PGR | |
| SCHEMBL2344031 | 0.83 | XDH (0.53) | XDHSLC22A12ABCC4ABCB11PGR | |
| SCHEMBL31602 | 0.82 | XDH (0.52) | XDHSLC22A12ABCC4ABCB11PGR | |
| SCHEMBL31571 | 0.82 | AAK1 (0.57) | XDHSLC22A12 | |
| SCHEMBL6052309 | 0.82 | ALDH1A1 (0.63) | XDHSLC22A12 | |
| SCHEMBL301279 | 0.82 | XDH (0.52) | XDHSLC22A12ABCC4ABCB11PGR | |
| SCHEMBL20195705 | 0.81 | XDH (0.47) | XDH | |
| SCHEMBL17708376 | 0.81 | ALDH1A1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140228417-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF SUBSTITUTED 2-ARYLTHIAZOLE CARBOXYLIC ACIDS | MAPI PHARMA LTD. (IL) | 2014-08-14 | — | — | US | disclosed |
| WO-2013050996-A2 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF SUBSTITUTED 2-ARYLTHIAZOLE CARBOXYLIC ACIDS | MAPI PHARMA LTD. (IL) | 2013-04-11 | — | — | WO | disclosed |
| WO-2010098428-A1 | PROCESS FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE THROUGH COUPLING USING TRANSITION METAL CATALYST | 帝人ファーマ株式会社 (JP) | 2010-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140228417-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF SUBSTITUTED 2-ARYLTHIAZOLE CARBOXYLIC ACIDS | XDH, NLRP3, PNPO | XDH 1/4885SLC22A12 1390/4885ABCC4 2113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.