Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6053677 | 0.98 | TDP1 (0.45) | TDP1PSIP1KCNH2EPHX2PKM | |
| SCHEMBL6053474 | 0.93 | TDP1 (0.46) | TDP1PSIP1HTR7ABCB1ALDH1A1 | |
| SCHEMBL6053419 | 0.86 | PSIP1 (0.47) | TDP1PSIP1PKMHTR7ALDH1A1 | |
| SCHEMBL6053266 | 0.82 | CES1 (0.47) | KCNH2ALDH1A1 | |
| SCHEMBL6053628 | 0.82 | CES1 (0.47) | KCNH2ALDH1A1 | |
| SCHEMBL6053420 | 0.80 | ALDH1A1 (0.46) | KCNH2ALDH1A1 | |
| SCHEMBL534941 | 0.80 | ALDH1A1 (0.44) | TDP1EPHX2PKMALDH1A1TSHR | |
| SCHEMBL25062242 | 0.79 | TDP1 (0.46) | TDP1PSIP1HTR7ABCB1ALDH1A1 | |
| SCHEMBL6053330 | 0.78 | PSIP1 (0.50) | TDP1PSIP1ALDH1A1TSHR | |
| SCHEMBL6053298 | 0.78 | ALDH1A1 (0.47) | KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7119232-B2 | Nucleophilic substitution reactions of difluorormethyl phenyl sulfone with alkyl halides leading to the facile synthesis of terminal 1,1-difluoro-1-alkenes and difluoromethylalkanes | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2006-10-10 | — | — | US | disclosed |
| US-20060052643-A1 | Nucleophilic substitution reactions of difluorormethyl phenyl sulfone with alkyl halides leading to the facile synthesis of terminal 1,1-difluoro-1-alkenes and difluoromethylalkanes | UNIVERSITY OF SOUTHERN CALIFORNIA | 2006-03-09 | — | — | US | disclosed |
| WO-2005097739-A2 | NUCLEOPHILIC SUBSTITUTION REACTIONS OF DIFLUOROMETHYL PHENYL SULFONE WITH ALKYL HALIDES LEADING TO THE FACILE SYNTHESIS OF TERMINAL 1,1-DIFLUORO-1-ALKENES AND DIFLUOROMETHYLALKANES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052643-A1 | Nucleophilic substitution reactions of difluorormethyl phenyl sulfone with alkyl halides leading to the facile synthesis of terminal 1,1-difluoro-1-alkenes and difluoromethylalkanes | PFAS, FRK, PFKFB1 | TDP1 1526/4885PSIP1 1415/4885KCNH2 337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.