Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8367520 | 0.89 | BACE1 (0.54) | ALOX5TSHRBACE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5305256 | 0.88 | TSHR (0.52) | ALOX5TSHRBACE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30269780 | 0.86 | CA2 (0.59) | ALOX5BACE1ALDH1A1HSD17B10HPGD | |
| 2-Phenylphenol SCHEMBL11847023 | 0.85 | ALDH1A1 (0.59) | ALOX5TSHRBACE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9766541 | 0.85 | TSHR (0.54) | TSHRSMN1; SMN2ALDH1A1HDAC6SNCA | |
| SCHEMBL9766558 | 0.85 | TSHR (0.54) | TSHRSMN1; SMN2ALDH1A1HDAC6SNCA | |
| SCHEMBL28971555 | 0.85 | ALOX5 (0.52) | ALOX5BACE1ALDH1A1HSD17B10HPGD | |
| SCHEMBL7408087 | 0.83 | TSHR (0.47) | TSHRBACE1SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL7609573 | 0.83 | ALDH1A1 (0.55) | TSHRSMN1; SMN2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL27680510 | 0.83 | TSHR (0.47) | TSHRSMN1; SMN2ALDH1A1HSD17B10BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015183931-A1 | STABILIZED CHEMILUMINESCENT SYSTEM | LI-COR, INC. (US) | 2015-12-03 | — | — | WO | claimed |
| EP-1682499-A1 | 4-BIARYLYL-1-PHENYLAZETIDIN-2-ONES | Microbia, Inc. (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005047248-A1 | 4-BIARYLYL-1-PHENYLAZETIDIN-2-ONES | MICROBIA, INC. (US) | 2005-05-26 | — | — | WO | disclosed |