Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766541 | 1.00 | TSHR (0.54) | TSHRSMN1; SMN2PTGS2POLBCYP2D6 | |
| SCHEMBL5305256 | 0.96 | TSHR (0.52) | TSHRSMN1; SMN2PTGS2POLBCYP2D6 | |
| SCHEMBL11293217 | 0.92 | LMNA (0.48) | TSHRSMN1; SMN2PTGS2POLBCYP2D6 | |
| SCHEMBL9766560 | 0.89 | TSHR (0.50) | TSHRSMN1; SMN2PTGS2POLBCYP2D6 | |
| SCHEMBL8602839 | 0.89 | ALDH1A1 (0.47) | TSHRSMN1; SMN2PTGS2HDAC6CA12 | |
| SCHEMBL8597478 | 0.88 | PTGS2 (0.64) | TSHRSMN1; SMN2PTGS2POLBCYP2D6 | |
| SCHEMBL25616078 | 0.85 | SMN1; SMN2 (0.46) | TSHRSMN1; SMN2PTGS2POLBCYP2D6 | |
| SCHEMBL25613460 | 0.85 | SMN1; SMN2 (0.46) | TSHRSMN1; SMN2PTGS2POLBCYP2D6 | |
| SCHEMBL6053296 | 0.85 | ALOX5 (0.55) | TSHRSMN1; SMN2PTGS2POLBCYP2D6 | |
| SCHEMBL25868039 | 0.84 | TSHR (0.44) | TSHRSMN1; SMN2PTGS2POLBCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008472-A | Preparation of 4,4\"-dihydroxyterphenyl | BASF AKTIENGESELLSCHAFT (DE) | 1991-04-16 | — | — | US | disclosed |