Indene

Indene

SCHEMBL6053299

C1=Cc2ccccc2C1.C=Cc1ccc(OC(=O)CCC)cc1.C=Cc1ccccc1O

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BCL9 O00512 1/20 0.34
CTNNB1 P35222 1/20 0.34
KMT2A Q03164 4/20 0.32
ESR1 P03372 3/20 0.31
PDGFRB P09619 1/20 0.31
PDGFRA P16234 1/20 0.31
EGFR P00533 1/20 0.31
ERBB2 P04626 1/20 0.31
HPGD P15428 1/20 0.31
CA2 P00918 1/20 0.31
LMNA P02545 1/20 0.31
IAPP P10997 1/20 0.30
MEN1 O00255 2/20 0.30
MAPT P10636 2/20 0.30
ALDH1A1 P00352 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indene SCHEMBL6053279 0.94 KMT2A (0.36) KMT2AESR1EGFRERBB2HPGD
Indene SCHEMBL6053478 0.92 ELANE (0.37) KMT2AESR1LMNAMEN1MAPT
Indene SCHEMBL6053432 0.87 MAPT (0.39) KMT2ALMNAMEN1MAPTALDH1A1
Indene SCHEMBL6053387 0.83 ELANE (0.37) CA2
Indene SCHEMBL15048570 0.82 RELA (0.40) KMT2AHPGDLMNAMEN1MAPT
Indene SCHEMBL6835844 0.80 MEN1 (0.39) KMT2AHPGDLMNAMEN1MAPT
Indene SCHEMBL15048613 0.80 CYP2C19 (0.39) CA2MAPT
Indene SCHEMBL2773974 0.79
Indene SCHEMBL546792 0.77 CYP2D6 (0.39) CA2ALDH1A1
Indene SCHEMBL1972484 0.77 MAPT (0.35) KMT2ACA2MEN1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060166133-A1 Negative resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-07-27 US disclosed