Indene

Indene

SCHEMBL15048613

C1=Cc2ccccc2C1.C=Cc1ccc(C)cc1.C=Cc1ccccc1O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.39
CYP2D6 P10635 1/20 0.39
MAPT P10636 1/20 0.33
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
FGF23 Q9GZV9 1/20 0.31
NFE2L2 Q16236 1/20 0.31
TRPA1 O75762 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indene SCHEMBL546792 0.89 CYP2D6 (0.39) CYP2C19CYP2D6CA1CA2NFE2L2
Indene SCHEMBL1972484 0.89 MAPT (0.35) CYP2C19CYP2D6MAPTCA1CA2
Indene SCHEMBL15048570 0.88 RELA (0.40) CYP2C19CYP2D6MAPTNFE2L2TRPA1
Indene SCHEMBL6053432 0.84 MAPT (0.39) CYP2C19CYP2D6MAPTCYP3A4
SCHEMBL15048547 0.83 MAPT (0.42) MAPTCA2FGF23NFE2L2TRPA1
Indene SCHEMBL6053478 0.81 ELANE (0.37) CYP2C19CYP2D6MAPT
Indene SCHEMBL2770682 0.81 CYP2D6 (0.30) CYP2C19CYP2D6
Indene SCHEMBL3141069 0.81 CYP2D6 (0.39) CYP2C19CYP2D6CA1CA2NFE2L2
Indene SCHEMBL8048473 0.80 ALDH1A1 (0.39) CYP2C19CYP2D6MAPTCA1CA2
Indene SCHEMBL6053387 0.80 ELANE (0.37) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8470509-B2 Negative resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-06-25 US disclosed