Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6053505 | 0.87 | NPSR1 (0.45) | NPC1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6053640 | 0.86 | KMT2A (0.43) | NPC1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL132989 | 0.82 | WDR5 (0.44) | TSHRMAPK1POLBMAPTTDP1 | |
| SCHEMBL29382484 | 0.82 | WDR5 (0.44) | TSHRMAPK1POLBMAPTTDP1 | |
| SCHEMBL29512053 | 0.80 | NPC1 (0.60) | NPC1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30237970 | 0.79 | MEN1 (0.60) | NPC1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6053720 | 0.77 | KEAP1 (0.49) | RAB9ACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7025867 | 0.76 | KMT2A (0.42) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL28582487 | 0.75 | NPC1 (0.57) | NPC1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28554239 | 0.75 | ADORA3 (0.59) | NPC1RAB9ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1469004-B1 | Method for preparing aminophosphines and aminophosphine oxides, intermediates therefor | TAKASAGO PERFUMERY CO LTD (JP) | 2006-06-14 | — | — | EP | disclosed |
| EP-1013658-B1 | Aminophosphine-metal complex for asymmetric reactions | TAKASAGO PERFUMERY CO LTD (JP) | 2004-11-03 | — | — | EP | disclosed |
| EP-1469004-A1 | Method for preparing aminophosphines and aminophosphine oxides, intermediates therefor | Takasago International Corporation (JP) | 2004-10-20 | — | — | EP | disclosed |
| US-6515156-B2 | Stereoselective, efficient catalyst for synthesis of enantiomerically pure compounds; comprising compex of transition metal and aminophosphine ligand | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-02-04 | — | — | US | disclosed |
| US-6388130-B2 | ALKALINE HYDROGEN PEROXIDE TO OXIDIZE 2-CYANO-2'-DIARYL PHOSPHINYL-1,1'-BINAPHTHYL TO OBTAIN A 2-AMIDO DERIVATIVE, REACTED WITH A METAL ALKOXIDE AND BROMINE IN AN ALCOHOL TO A 2-SEC-AMINO DERIVATIVE; TRANSITION METAL COMPLEX CATALYSTS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-05-14 | — | — | US | disclosed |
| US-20010047110-A1 | Method for producing axial asymmetric compounds, intermediates for producing the same, complexes of transition metals with novel axial asymmetric compounds as the ligands, catalysts for asymmetric hydrogenation, and catalysts for forming asymmetric carbon-carbon bonds | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-11-29 | — | — | US | disclosed |
| US-6323353-B1 | USED AS CATALYST FOR ASYMMETRIC HYDROGENATION OR CARBON-CARBON BOND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-11-27 | — | — | US | disclosed |
| US-20010037033-A1 | Method for producing axial asymmetric compounds, intermediates for producing the same, complexes of transition metals with novel axial asymmetric compounds as the ligands, catalysts for asymmetric hydrogenation, and catalysts for forming asymmetric carbon-carbon bonds | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-11-01 | — | — | US | disclosed |
| EP-1013658-A1 | Aminophosphine-metal complex for asymmetric reactions | Takasago International Corporation (JP) | 2000-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010047110-A1 | Method for producing axial asymmetric compounds, intermediates for producing the same, complexes of transition metals with novel axial asymmetric compounds as the ligands, catalysts for asymmetric hydrogenation, and catalysts for forming asymmetric carbon-carbon bonds | CORO1C, AP3M1, ARL1 | NPC1 652/4885RAB9A 826/4885CYP1A2 1736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.