Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.47 |
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6053666 | 0.98 | MAOA (0.47) | MAPTRXFP1SIGMAR1FAAHCES1 | |
| SCHEMBL6053391 | 0.92 | HDAC3 (0.45) | MAPTRXFP1SIGMAR1MAOAMAOB | |
| SCHEMBL6053648 | 0.84 | TDP1 (0.46) | SIGMAR1HDAC1HDAC2ALOX15 | |
| SCHEMBL29291453 | 0.78 | MAOA (0.47) | MAPTRXFP1SIGMAR1MAOAMAOB | |
| SCHEMBL11829781 | 0.78 | MAPT (0.55) | MAPTRXFP1SIGMAR1FAAHCES1 | |
| SCHEMBL4889046 | 0.78 | SIGMAR1 (0.52) | MAPTRXFP1SIGMAR1FAAHCES1 | |
| SCHEMBL3586717 | 0.78 | MAPT (0.53) | MAPTRXFP1SIGMAR1MAOATRPV1 | |
| SCHEMBL4469893 | 0.78 | MAPT (0.53) | MAPTRXFP1SIGMAR1MAOATRPV1 | |
| SCHEMBL10516477 | 0.78 | MAPT (0.53) | MAPTRXFP1SIGMAR1MAOATRPV1 | |
| SCHEMBL3584640 | 0.78 | MAPT (0.53) | MAPTRXFP1SIGMAR1MAOATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7119232-B2 | Nucleophilic substitution reactions of difluorormethyl phenyl sulfone with alkyl halides leading to the facile synthesis of terminal 1,1-difluoro-1-alkenes and difluoromethylalkanes | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2006-10-10 | — | — | US | disclosed |
| US-20060052643-A1 | Nucleophilic substitution reactions of difluorormethyl phenyl sulfone with alkyl halides leading to the facile synthesis of terminal 1,1-difluoro-1-alkenes and difluoromethylalkanes | UNIVERSITY OF SOUTHERN CALIFORNIA | 2006-03-09 | — | — | US | disclosed |
| WO-2005097739-A2 | NUCLEOPHILIC SUBSTITUTION REACTIONS OF DIFLUOROMETHYL PHENYL SULFONE WITH ALKYL HALIDES LEADING TO THE FACILE SYNTHESIS OF TERMINAL 1,1-DIFLUORO-1-ALKENES AND DIFLUOROMETHYLALKANES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052643-A1 | Nucleophilic substitution reactions of difluorormethyl phenyl sulfone with alkyl halides leading to the facile synthesis of terminal 1,1-difluoro-1-alkenes and difluoromethylalkanes | PFAS, FRK, PFKFB1 | MAPT 4421/4885RXFP1 4451/4885SIGMAR1 2940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.