Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5168421 | 0.87 | ALDH1A1 (0.36) | ALDH1A1CYP1A2HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL5167142 | 0.85 | DHFR (0.35) | HTR1AHTR7ALDH1A1CYP1A2HPGD | |
| Hydrochloric Acid SCHEMBL27480139 | 0.80 | CES1 (0.37) | CES1HTR1AHTR7ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL5170137 | 0.80 | GSTP1 (0.36) | DHFR | |
| Hydrochloric Acid SCHEMBL5415129 | 0.78 | BRD4 (0.33) | HTR1AHTR7ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL27525742 | 0.77 | CES1 (0.35) | CES1HTR1AHTR7ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL6894585 | 0.76 | HTR1A (0.36) | CES1HTR1AHTR7ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL6895703 | 0.76 | HTR1A (0.39) | CES1HTR1AHTR7ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL6893657 | 0.76 | HTR1A (0.36) | CES1HTR1AHTR7ALDH1A1CYP1A2 | |
| SCHEMBL27464559 | 0.75 | CES1 (0.35) | CES1HTR1AHTR7ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005398-B2 | Olefin polymerization catalyst, catalyst component for olefin polymerization, method of storing these, and process for producing olefin polymer | SUNALLOMER LTD. (JP) | 2006-02-28 | — | — | US | disclosed |
| US-20040054102-A1 | Olefin polymerization catalyst, catalyst component for olefin polymerization, method of storing these, and process for producing olefin polymer | SUNALLOMER LTD. (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1359166-A1 | OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, METHOD OF STORING THESE, AND PROCESS FOR PRODUCING OLEFIN POLYMER | Sunallomer Ltd (JP) | 2003-11-05 | — | — | EP | disclosed |