SCHEMBL6058682

SCHEMBL6058682

CC(=O)Oc1nc(Cl)c(Cl)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.50
KMT2A Q03164 4/20 0.50
MEN1 O00255 3/20 0.50
ALDH1A1 P00352 5/20 0.46
CYP3A4 P08684 3/20 0.46
ALOX12 P18054 2/20 0.46
MAPT P10636 2/20 0.46
HSD17B10 Q99714 2/20 0.46
MAPK1 P28482 2/20 0.46
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALOX5 P09917 1/20 0.35
KDM4E B2RXH2 3/20 0.34
GLA P06280 3/20 0.33
LMNA P02545 3/20 0.33
GAA P10253 2/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10999122 0.82 TDP1 (0.47) TDP1KMT2AMEN1ALDH1A1CYP3A4
SCHEMBL10749607 0.81 KMT2A (0.51) TDP1KMT2AMEN1ALDH1A1CYP3A4
SCHEMBL8734591 0.81 TDP1 (0.44) TDP1KMT2AMEN1ALDH1A1CYP3A4
SCHEMBL9488826 0.78 TDP1 (0.44) TDP1KMT2AMEN1ALDH1A1CYP3A4
SCHEMBL32670815 0.78 TDP1 (0.41) TDP1KMT2AMEN1ALDH1A1CYP3A4
SCHEMBL12786974 0.77 TDP1 (0.43) TDP1KMT2AMEN1ALDH1A1CYP3A4
SCHEMBL1462677 0.74 ALDH1A1 (0.47) TDP1KMT2AMEN1ALDH1A1MAPT
Triclopyr SCHEMBL23633000 0.74 KDM4E (0.45) TDP1KMT2AMEN1ALDH1A1CYP3A4
SCHEMBL10851855 0.74 KMT2A (0.46) TDP1KMT2AMEN1ALDH1A1MAPT
SCHEMBL27567589 0.73 CRHBP (0.50) TDP1KMT2AMEN1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210400957-A1 AUXIN HERBICIDE AND L-GLUFOSINATE MIXTURES MONSANTO TECHNOLOGY LLC 2021-12-30 US claimed
WO-2019158601-A1 LOW VOLATILITY HERBICIDAL COMPOSITIONS RHODIA OPERATIONS (FR) 2019-08-22 WO claimed
EP-2934122-A1 AUXIN HERBICIDAL MIXTURES Monsanto Technology LLC (US) 2015-10-28 EP claimed
WO-2014071348-A1 AUXIN HERBICIDAL MIXTURES MONSANTO TECHNOLOGY LLC (US) 2014-05-08 WO claimed
JP-55094309-A None JP disclosed
US-20240164377-A1 LOW VOLATILITY PROMOTING WATER CONDITIONING ADJUVANTS ADJUVANTS UNLIMITED LLC (US) 2024-05-23 US disclosed
US-11109591-B2 Single phase liquids of alkanolamine salts of dicamba TAMINCO BVBA (BE) 2021-09-07 US disclosed
EP-3788012-A1 COMPOSITIONS FOR CONTROLLING PHYTOPLANKTON CONTAMINATION BlueGreen Water Technologies Ltd. (IL) 2021-03-10 EP disclosed
WO-2020161696-A1 COMPOSITIONS FOR CONTROLLING PHYTOPLANKTON CONTAMINATION BLUEGREEN WATER TECHNOLOGIES LTD. (IL) 2020-08-13 WO disclosed
EP-3614844-A1 HIGHLY CONCENTRATED SOLUTIONS OF ALKANOLAMINE SALTS OF DICAMBA Taminco BVBA (BE) 2020-03-04 EP disclosed
WO-2018197418-A1 HIGHLY CONCENTRATED SOLUTIONS OF ALKANOLAMINE SALTS OF DICAMBA TAMINCO BVBA (BE) 2018-11-01 WO disclosed
US-20180303091-A1 SINGLE PHASE LIQUIDS OF ALKANOLAMINE SALTS OF DICAMBA TAMINCO BVBA (BE) 2018-10-25 US disclosed
WO-1990009383-A1 HERBICIDAL OXABICYCLONONANE ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-08-23 WO disclosed
US-4552584-A ANTIBIOTIS SF-1293 MEIJI SEIKA KAISHA, LTD. (JP) 1985-11-12 US disclosed
US-4309208-A ANTIBIOTIC SF-1293 MEIJI SEIKA KAISHA, LTD. (JP) 1982-01-05 US disclosed
US-4263037-A 5-Cyano-2,3-dihydrobenzofurans useful as herbicides FISONS LIMITED (GB) 1981-04-21 US disclosed
US-4222767-A Certain herbicidal sulfonates and sulfamates FISONS LIMITED (GB) 1980-09-16 US disclosed
JP-S5594309-A HERBICIDE COMPOSITION NISSAN CHEM IND LTD 1980-07-17 JP disclosed
EP-0007719-A2 Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives FBC LIMITED (GB) 1980-02-06 EP disclosed
US-4183741-A POSTEMERGENCE FISONS LIMITED (GB) 1980-01-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210400957-A1 AUXIN HERBICIDE AND L-GLUFOSINATE MIXTURES GLUL, PIK3C3, AGXT TDP1 392/4885KMT2A 2149/4885MEN1 3411/4885
US-11109591-B2 Single phase liquids of alkanolamine salts of dicamba ALK, ALKBH3, SLC43A1 TDP1 2429/4885KMT2A 109/4885MEN1 4354/4885
US-20180303091-A1 SINGLE PHASE LIQUIDS OF ALKANOLAMINE SALTS OF DICAMBA ALK, ALKBH3, SLC43A1 TDP1 2429/4885KMT2A 109/4885MEN1 4354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.