SCHEMBL6058853

SCHEMBL6058853

O=C(Nc1ccccc1Oc1ccccc1)c1ccc(Cl)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.72
LMNA P02545 2/20 0.72
SMN1; SMN2 Q16637 2/20 0.72
KMT2A Q03164 4/20 0.68
NPC1 O15118 3/20 0.68
RAB9A P51151 3/20 0.68
TP53 P04637 3/20 0.68
NR1I2 O75469 1/20 0.68
AHR P35869 1/20 0.68
TAAR1 Q96RJ0 1/20 0.68
TDP1 Q9NUW8 2/20 0.61
MEN1 O00255 3/20 0.60
SERPINE1 P05121 1/20 0.60
CACNA1H O95180 2/20 0.59
CACNA1B Q00975 1/20 0.59
CASP3 P42574 1/20 0.58
SENP8 Q96LD8 1/20 0.58
SENP7 Q9BQF6 1/20 0.58
SENP6 Q9GZR1 1/20 0.58
MDM4 O15151 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27716651 0.93 L3MBTL1 (0.64) L3MBTL1LMNASMN1; SMN2KMT2ANPC1
SCHEMBL27943418 0.89 MAPT (0.67) L3MBTL1LMNASMN1; SMN2KMT2ARAB9A
SCHEMBL2890785 0.88 PYGL (0.60) L3MBTL1LMNASMN1; SMN2KMT2ANPC1
SCHEMBL96335 0.85 MAPT (0.60) L3MBTL1LMNASMN1; SMN2RAB9ATDP1
SCHEMBL7125502 0.85 PYGM (0.79) L3MBTL1LMNASMN1; SMN2KMT2ANPC1
SCHEMBL12190105 0.85 SMN1; SMN2 (0.60) L3MBTL1LMNASMN1; SMN2TDP1CACNA1H
SCHEMBL27716717 0.84 CACNA1H (0.60) L3MBTL1LMNASMN1; SMN2KMT2ARAB9A
SCHEMBL27716773 0.82 PYGM (0.63) L3MBTL1LMNASMN1; SMN2KMT2ANPC1
SCHEMBL4060914 0.82 KCNQ3 (0.65) L3MBTL1LMNASMN1; SMN2KMT2ATP53
SCHEMBL11439725 0.81 ALDH1A1 (0.71) LMNASMN1; SMN2KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1138712-B1 Polyarylene copolymers and proton-conductive membrane JSR CORP (JP) 2006-01-18 EP disclosed
US-6555626-B2 Controlled amount of sulfonic acid groups; copolymer of an aromatic compound having a main chain containing electron withdrawing groups and aromatic compounds with no electron withdrawing groups; durability, strength, conductivity JSR CORPORATION (JP) 2003-04-29 US disclosed
EP-1245554-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR Corporation (JP) 2002-10-02 EP disclosed
US-20010037000-A1 Polyarylene copolymers and proton-conductive membrane JSR CORPORATION (JP) 2001-11-01 US disclosed