Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6059446 | 0.96 | CPB2 (0.41) | CPB2PPARGL3MBTL1MKNK2MEN1 | |
| Malonic Acid Diethyl Ester SCHEMBL7380709 | 0.92 | L3MBTL1 (0.41) | CPB2PPARGL3MBTL1MKNK2MEN1 | |
| SCHEMBL6059454 | 0.88 | MEN1 (0.35) | CPB2PPARGL3MBTL1MKNK2MEN1 | |
| SCHEMBL6058628 | 0.87 | PPARG (0.39) | PPARGL3MBTL1MKNK2ALDH1A1PKM | |
| SCHEMBL6058861 | 0.82 | CPB2 (0.42) | CPB2PPARGL3MBTL1MKNK2MEN1 | |
| SCHEMBL6058797 | 0.82 | PPARG (0.36) | CPB2PPARGL3MBTL1MKNK2ALDH1A1 | |
| SCHEMBL6059170 | 0.79 | NAMPT (0.43) | CPB2PPARGMKNK2ALDH1A1PKM | |
| SCHEMBL6059152 | 0.79 | STK17B (0.42) | L3MBTL1MEN1KMT2AALDH1A1MAPT | |
| Malonic Acid Diethyl Ester SCHEMBL7380431 | 0.79 | PPARG (0.36) | CPB2PPARGL3MBTL1MKNK2ALDH1A1 | |
| SCHEMBL6059420 | 0.79 | L3MBTL1 (0.38) | PPARGL3MBTL1MKNK2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071175-B1 | Pyridine mercapto carboxylic acids as carboxypeptidase U inhibitors | ASTRAZENECA AB (SE) | 2006-07-04 | — | — | US | disclosed |
| EP-1180098-A1 | NEW COMPOUNDS | AstraZeneca AB (SE) | 2002-02-20 | — | — | EP | disclosed |
| WO-2000066557-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 2000-11-09 | — | — | WO | disclosed |