Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29024081 | 0.84 | CA2 (0.54) | HPGDCA1CA2TP53TSHR | |
| SCHEMBL9344917 | 0.82 | TSHR (0.52) | HPGDCA1CA2TP53TSHR | |
| SCHEMBL6062136 | 0.80 | CASP1 (0.40) | CA1CA2TP53TSHRCASP1 | |
| SCHEMBL7026614 | 0.80 | NCOA1 (0.58) | CA1CA2TP53TSHRL3MBTL1 | |
| SCHEMBL7545091 | 0.80 | TRPA1 (0.48) | HPGDCA1CA2TP53TSHR | |
| SCHEMBL13995152 | 0.79 | ALDH1A1 (0.49) | HPGDXBP1TSHRCASP1L3MBTL1 | |
| SCHEMBL13160049 | 0.79 | SLC6A4 (0.54) | HPGDXBP1CASP1L3MBTL1ALDH1A1 | |
| SCHEMBL15472269 | 0.79 | HTT (0.73) | HPGDXBP1CA1CA2TSHR | |
| SCHEMBL5018840 | 0.79 | XIAP (0.54) | HPGDXBP1CASP1L3MBTL1ALDH1A1 | |
| SCHEMBL4517427 | 0.79 | ALDH1A1 (0.46) | TSHRALDH1A1HTTTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105577-B2 | for finishing of undyed and dyed or printed fibre materials; treatment of skin, mucous membrane or hair, hard surfaces, oral care; detergent | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-09-12 | — | — | US | disclosed |