Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5599308 | 0.86 | ACHE (0.42) | BCHEACHEHTR6 | |
| Hydrochloric Acid SCHEMBL30568155 | 0.86 | ACHE (0.42) | BCHEACHEHTR6 | |
| Hydrochloric Acid SCHEMBL6062220 | 0.80 | KDM4E (0.31) | HTR6 | |
| Hydrochloric Acid SCHEMBL28827229 | 0.75 | BCHE (0.32) | BCHEACHE | |
| SCHEMBL6062011 | 0.75 | HTR6 (0.35) | BCHEACHEHTR6 | |
| Hydrochloric Acid SCHEMBL28375726 | 0.74 | HTR6 (0.33) | BCHEACHEHTR6 | |
| Hydrochloric Acid SCHEMBL2805340 | 0.74 | HTR6 (0.33) | BCHEACHEHTR6 | |
| Hydrochloric Acid SCHEMBL6061661 | 0.74 | HTR6 (0.32) | HTR6 | |
| Hydrochloric Acid SCHEMBL28506062 | 0.73 | HTR6 (0.38) | BCHEACHEHTR6 | |
| SCHEMBL28337780 | 0.71 | HTR6 (0.39) | BCHEACHEHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060142147-A1 | Catalysts compositions for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA, S.A. (ES) | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142147-A1 | Catalysts compositions for the polymerization and copolymerization of alpha-olefins | B2M, OPRM1, POLM | ACHE 2280/4885BCHE 2063/4885HTR6 1387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.