SCHEMBL60623

SCHEMBL60623

C=Cc1cccc(OC)c1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR2 O60603 1/20 0.67
ERN1 O75460 1/20 0.67
TLR1 Q15399 1/20 0.67
TLR6 Q9Y2C9 1/20 0.67
CA12 O43570 1/20 0.59
MAPT P10636 7/20 0.57
KDM4E B2RXH2 5/20 0.57
LMNA P02545 2/20 0.57
MAPK1 P28482 2/20 0.57
ALDH1A1 P00352 1/20 0.57
TP53 P04637 1/20 0.57
CYP3A4 P08684 1/20 0.57
HPGD P15428 1/20 0.57
ALOX15 P16050 1/20 0.57
ALOX12 P18054 1/20 0.57
HSD17B10 Q99714 1/20 0.57
ABL1 P00519 1/20 0.54
ABCB1 P08183 1/20 0.54
BCR P11274 1/20 0.54
NPC1 O15118 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL28629154 0.81 ERN1 (0.93) TLR2ERN1TLR1TLR6CA12
SCHEMBL30485148 0.80 ERN1 (1.00) TLR2ERN1TLR1TLR6CA12
SCHEMBL11469615 0.80 TLR2 (0.67) TLR2ERN1TLR1TLR6CA12
SCHEMBL16004 0.80 ERN1 (1.00) TLR2ERN1TLR1TLR6CA12
SCHEMBL929734 0.80 ERN1 (1.00) TLR2ERN1TLR1TLR6CA12
SCHEMBL10054715 0.80 TLR2 (0.67) TLR2ERN1TLR1TLR6CA12
SCHEMBL27656312 0.79 MAPT (0.51) TLR2ERN1TLR1TLR6CA12
SCHEMBL7990624 0.79 TLR2 (0.46) TLR2ERN1TLR1TLR6CA12
SCHEMBL14909 0.79 NFE2L2 (0.55) CA12MAPTKDM4ELMNAALDH1A1
SCHEMBL29377009 0.79 NFE2L2 (0.55) CA12MAPTKDM4ELMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4003058-A1 NATURAL VANILLIN COMPOSITIONS RHODIA OPERATIONS (FR) 2022-06-01 EP claimed
US-7803846-B2 Highly durable polymer electrolytic membrane for a fuel cell having a cross-linked structure JAPAN ATOMIC ENERGY AGENCY (JP) 2010-09-28 US claimed
US-20060134493-A1 Highly durable polymer electrolytic membrane for a fuel cell having a cross-linked structure JAPAN ATOMIC ENERGY AGENCY (JP) 2006-06-22 US claimed
EP-4103144-B1 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2026-05-27 EP disclosed
WO-2026087745-A1 AN ANTIOXIDANT COMPOSITION COMPRISING A CINNAMIC ACID DERIVATIVE BRAIN Biotech AG (DE) 2026-04-30 WO disclosed
EP-4732825-A1 AN ANTIOXIDANT COMPOSITION COMPRISING A CINNAMIC ACID DERIVATIVE BRAIN Biotech AG (DE) 2026-04-29 EP disclosed
EP-4110277-B1 COMPOSITIONS COMPRISING (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2026-04-22 EP disclosed
US-20260096978-A1 A METHOD FOR PREVENTING, MITIGATING AND/OR TREATING PTGS2-INDUCED SKIN DISORDERS AND RELATED DYSFUNCTIONS SYMRISE AG (DE) 2026-04-09 US disclosed
EP-3045161-B1 Use of active mixtures of 1,2-hexanediol and 1,2-octanediol in cosmetic, pharmaceutical or dermatological emulsions SYMRISE AG (DE) 2026-03-25 EP disclosed
EP-4025675-B1 A PERFUME OIL MIXTURE SYMRISE AG (DE) 2026-03-18 EP disclosed
EP-4706780-A2 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS Symrise AG (DE) 2026-03-11 EP disclosed
US-20070224480-A1 Process for producing polymer electrolyte membranes for fuel cells, polymer electrolyte membranes for fuel cells produced by the process, and fuel cell membrane-electrode assemblies using the membranes JAPAN ATOMIC ENERGY AGENCY (JP) 2007-09-27 US disclosed
US-20070207359-A1 Crosslinked nano-inorganic particle/polymer electrolyte membrane and method for producing same, and membrane electrode assembly using same JAPAN ATOMIC ENERGY AGENCY (JP) 2007-09-06 US disclosed
EP-1742286-A1 Crosslinked polymer electrolyte fuel cell membranes and their producing process Japan Atomic Energy Agency (JP) 2007-01-10 EP disclosed
US-20060281824-A1 Crosslinked polymer electrolyte fuel cell membranes and their producing process JAPAN ATOMIC ENERGY AGENCY (JP) 2006-12-14 US disclosed
US-20060258714-A1 Chromane and chromene derivatives and uses thereof WYETH (US) 2006-11-16 US disclosed
WO-2006116165-A1 CHROMANE AND CHROMENE DERIVATIVES AND USES THEREOF WYETH (US) 2006-11-02 WO disclosed
US-20060134493-A1 Highly durable polymer electrolytic membrane for a fuel cell having a cross-linked structure JAPAN ATOMIC ENERGY AGENCY (JP) 2006-06-22 US disclosed
CN-1246461-C Method for compositions for modifying levels of secondary metabolic compounds in plants CA NAT RESEARCH COUNCIL (CA) 2006-03-22 CN disclosed
CN-1292822-A Method for compositions for modifying levels of secondary metabolic compounds in plants CA NAT RESEARCH COUNCIL (CA) 2001-04-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060258714-A1 Chromane and chromene derivatives and uses thereof HTR1A, HTR2C, CHRM1 TLR2 658/4885ERN1 3054/4885TLR1 688/4885
US-20260096978-A1 A METHOD FOR PREVENTING, MITIGATING AND/OR TREATING PTGS2-INDUCED SKIN DISORDERS AND RELATED DYSFUNCTIONS PTGS2, PTGES2, PTGS1 TLR2 251/4885ERN1 3740/4885TLR1 320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.