Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567088 | 0.86 | MEN1 (0.51) | SMN1; SMN2MEN1KMT2AALDH1A1ATM | |
| SCHEMBL10322782 | 0.81 | KMT2A (0.47) | SMN1; SMN2MEN1KMT2AALDH1A1ATM | |
| SCHEMBL14511670 | 0.81 | ALDH1A1 (0.45) | SMN1; SMN2MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL1119176 | 0.81 | CES2 (0.59) | CES2CES1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL20787058 | 0.78 | KDM4E (0.42) | CES2CES1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4755209 | 0.78 | CES2 (0.55) | CES2CES1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5578230 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL23112434 | 0.77 | POLB (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1ATM | |
| SCHEMBL497796 | 0.77 | ACHE (0.46) | CES2CES1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15730010 | 0.75 | SMN1; SMN2 (0.45) | SMN1; SMN2MEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078363-B2 | Olefin polymerisation catalyst | ARKEMA (FR) | 2006-07-18 | — | — | US | disclosed |
| US-20040097672-A1 | Olefin polymerisation catalyst | TOTAL PETROCHEMICALS FRANCE (FR) | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097672-A1 | Olefin polymerisation catalyst | AS3MT, SOD1, SCO2 | CES2 3043/4885CES1 4269/4885SMN1; SMN2 2095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.