Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | IL1B | P01584 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6063896 | 1.00 | GRM1 (0.39) | GRM1TDP1KMT2AMEN1CYP1A2 | |
| SCHEMBL14433087 | 0.81 | TSHR (0.46) | BLMNPSR1TSHRPOLBPKM | |
| SCHEMBL3147639 | 0.79 | GRM1 (0.40) | GRM1TDP1KMT2AMEN1CYP1A2 | |
| SCHEMBL27646821 | 0.78 | LMNA (0.35) | GRM1TDP1KMT2AMEN1CYP1A2 | |
| SCHEMBL7629389 | 0.77 | GRM1 (0.42) | GRM1TDP1KMT2AMEN1CYP1A2 | |
| SCHEMBL7395695 | 0.77 | LMNA (0.41) | TDP1KMT2AMEN1CYP1A2LMNA | |
| SCHEMBL7395691 | 0.77 | LMNA (0.41) | TDP1KMT2AMEN1CYP1A2LMNA | |
| SCHEMBL654108 | 0.74 | TSHR (0.50) | GRM1TDP1KMT2AMEN1CYP1A2 | |
| SCHEMBL7949922 | 0.73 | KDM4E (0.40) | GRM1TDP1KMT2AMEN1CYP1A2 | |
| SCHEMBL10770592 | 0.72 | CYP3A4 (0.35) | MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019166-B2 | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2006-03-28 | — | — | US | claimed |
| US-20050182274-A1 | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2005-08-18 | — | — | US | claimed |
| US-7019166-B2 | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2006-03-28 | — | — | US | disclosed |
| US-7019166-B2 | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2006-03-28 | — | — | US | disclosed |
| CN-1659129-A | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2005-08-24 | — | — | CN | disclosed |
| US-20050182274-A1 | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2005-08-18 | — | — | US | disclosed |
| US-20050182274-A1 | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2005-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182274-A1 | Method for the production of 2,4,5-trimethylphenyl acetic acid | CA6, DDC, HACL2 | GRM1 3154/4885TDP1 4225/4885KMT2A 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.