Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | IL1B | P01584 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LDHA | P00338 | 2/20 | 0.32 |
| ▸ | LDHB | P07195 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TPMT | P51580 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6063896 | 0.79 | GRM1 (0.39) | GRM1TDP1MEN1KMT2ACYP1A2 | |
| SCHEMBL7629389 | 0.79 | GRM1 (0.42) | GRM1TDP1MEN1KMT2ACYP1A2 | |
| SCHEMBL6063901 | 0.79 | GRM1 (0.39) | GRM1TDP1MEN1KMT2ACYP1A2 | |
| SCHEMBL5491706 | 0.76 | ALDH1A1 (0.42) | MEN1KMT2ASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL8706660 | 0.76 | SRC (0.49) | GRM1TDP1MEN1KMT2ACYP1A2 | |
| SCHEMBL11625901 | 0.73 | TSHR (0.51) | GRM1TDP1MEN1KMT2ACYP1A2 | |
| SCHEMBL21268924 | 0.70 | TDP1 (0.40) | GRM1TDP1MEN1KMT2ACYP1A2 | |
| SCHEMBL21269546 | 0.70 | TDP1 (0.40) | GRM1TDP1MEN1KMT2ACYP1A2 | |
| SCHEMBL21269396 | 0.70 | TDP1 (0.40) | GRM1TDP1MEN1KMT2ACYP1A2 | |
| Acetic Acid SCHEMBL28165166 | 0.70 | FFAR3 (0.50) | TDP1MEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567482-B1 | PROCESS FOR THE PREPARATION OF PHENYLMALONIC ACID DINITRILES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-02-17 | — | — | EP | disclosed |
| US-7268247-B2 | Process for the preparation of phenylmalonic acid dinitriles | SYNGENTA CROP PROTECTION, INC. (US) | 2007-09-11 | — | — | US | disclosed |
| US-7256158-B2 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | BAYER AG (DE) | 2007-08-14 | — | — | US | disclosed |
| US-7256158-B2 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | BAYER AG (DE) | 2007-08-14 | — | — | US | disclosed |
| US-7256158-B2 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | BAYER AG (DE) | 2007-08-14 | — | — | US | disclosed |
| US-20060135805-A1 | Process for the preparation of phenylmalonic acid dinitriles | SYNGENTA CROP PROTECTION, INC. | 2006-06-22 | — | — | US | disclosed |
| EP-1567482-A1 | PROCESS FOR THE PREPARATION OF PHENYLMALONIC ACID DINITRILES | Syngenta Participations AG (CH) | 2005-08-31 | — | — | EP | disclosed |
| US-6933261-B2 | 2,4,5-Trisubstituted phenylketoenols | BAYER AKTIENGESELLSCHAFT (DE) | 2005-08-23 | — | — | US | disclosed |
| US-20050038021-A1 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | BAYER AG (DE) | 2005-02-17 | — | — | US | disclosed |
| WO-2004050607-A1 | PROCESS FOR THE PREPARATION OF PHENYLMALONIC ACID DINITRILES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-06-17 | — | — | WO | disclosed |
| US-20030171219-A1 | 2,4,5-trisubstituted phenylketo-enols for use as pesticides and herbicides | LIEB FOLKER (DE) | 2003-09-11 | — | — | US | disclosed |
| US-6511942-B1 | Animal husbandry, veterinary medicine | BAYER AKTIENGESELLSCHAFT (DE) | 2003-01-28 | — | — | US | disclosed |
| EP-0837847-B1 | 2,4,5-TRISUBSTITUTED PHENYLKETO-ENOLS FOR USE AS PESTICIDES AND HERBICIDES | BAYER AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| US-6110872-A | 3-(2,4,5-TRISUBSTITUTED PHENYL), 4-HYDROXY,5,5-(CYCLOALKYL OR HETEROCYCLOALKYL)PYRROLIN-2-ONE AND DERIVATIVES; METHOD OF MAKING BY INTRAMOLECULAR CONDENSATION OF SPECIFIED COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-29 | — | — | US | disclosed |
| EP-0837847-A1 | 2,4,5-TRISUBSTITUTED PHENYLKETO-ENOLS FOR USE AS PESTICIDES AND HERBICIDES | BAYER AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997001535-A1 | 2,4,5-TRISUBSTITUTED PHENYLKETO-ENOLS FOR USE AS PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038021-A1 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | DDT, CYP4X1, PDHX | GRM1 1288/4885TDP1 2821/4885MEN1 4803/4885 |
| US-20030171219-A1 | 2,4,5-trisubstituted phenylketo-enols for use as pesticides and herbicides | DDT, CYP4X1, HPD | GRM1 756/4885TDP1 1958/4885MEN1 4719/4885 |
| US-20060135805-A1 | Process for the preparation of phenylmalonic acid dinitriles | ME1, PDK2, PDK4 | GRM1 3136/4885TDP1 4496/4885MEN1 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.