SCHEMBL6064263

SCHEMBL6064263

C=C(C(=O)O)C(F)(F)C(F)(F)CC

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL561206 0.79 TET2 (0.33) TET2
SCHEMBL4317323 0.77 TET2 (0.32) TET2
SCHEMBL2190106 0.76 TET2 (0.34) TET2
SCHEMBL6063629 0.76 TET2 (0.34) TET2
SCHEMBL23829806 0.75 ACLY (0.41)
SCHEMBL1735238 0.73 TET2 (0.33) TET2
Methacrylic Acid SCHEMBL4241822 0.73 TET2 (0.32) TET2
SCHEMBL22581591 0.72 THRB (0.32)
SCHEMBL7148036 0.72
SCHEMBL1416716 0.72 TET2 (0.38) TET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7148363-B2 Process for preparing acrylate compound TOSOH CORPORATION (JP) 2006-12-12 US disclosed
US-20050148789-A1 Process for preparing acrylate compound TOSOH CORPORATION 2005-07-07 US disclosed
US-6833462-B2 Esterification to get cyclic acrylate compounds; used as raw material for functional polymers, pharmaceuticals, pesticides, semiconductor lithography TOSOH CORPORATION (JP) 2004-12-21 US disclosed
US-20030139613-A1 Process for preparing acrylate compound TOSOH CORPORATION 2003-07-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139613-A1 Process for preparing acrylate compound AFF1, AFF4, RER1 TET2 1456/4885
US-20050148789-A1 Process for preparing acrylate compound ACR, AFF4, AFF1 TET2 1202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.