Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GPX4 | P36969 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680424 | 0.96 | NPC1 (0.49) | LTB4R2ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL1506356 | 0.83 | NPC1 (0.58) | LTB4R2ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL6064822 | 0.82 | ALDH1A1 (0.47) | LTB4R2ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL11651430 | 0.82 | RAB9A (0.63) | LTB4R2ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL28072408 | 0.82 | ALDH1A1 (0.52) | LTB4R2ALDH1A1KMT2ANR1H4HPGD | |
| Hydrochloric Acid SCHEMBL27532672 | 0.82 | NPC1 (0.56) | LTB4R2ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL8938088 | 0.81 | ALDH1A1 (0.46) | LTB4R2ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL10689801 | 0.79 | ALDH1A1 (0.47) | LTB4R2ALDH1A1KMT2ANR1H4HPGD | |
| SCHEMBL15020737 | 0.79 | PLA2G2A (0.45) | ALDH1A1NPC1RAB9APAX8TP53 | |
| SCHEMBL3055011 | 0.79 | NPC1 (0.65) | ALDH1A1NPC1RAB9APAX8TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560878-B1 | THERMALLY STABILISED PVC COMPOSITIONS | LAMBERTI SPA (IT) | 2006-05-17 | — | — | EP | disclosed |
| EP-1560878-A1 | THERMALLY STABILISED PVC COMPOSITIONS | Lamberti Spa (IT) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004046236-A1 | THERMALLY STABILISED PVC COMPOSITIONS | LAMBERTI SPA (IT) | 2004-06-03 | — | — | WO | disclosed |