Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.67 |
| ▸ | GSK3B | P49841 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6186324 | 0.98 | KMO (0.65) | KMOGSK3BKDM4EUSP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6538516 | 0.96 | KMO (0.63) | KMOGSK3BKDM4EUSP2ALDH1A1 | |
| SCHEMBL6374645 | 0.94 | KMO (0.61) | KMOGSK3BKDM4EUSP2ALDH1A1 | |
| SCHEMBL17737077 | 0.91 | KMO (0.57) | KMOGSK3BKDM4EUSP2ALDH1A1 | |
| SCHEMBL19831259 | 0.90 | MAPT (0.68) | KMOGSK3BKDM4EUSP2ALDH1A1 | |
| SCHEMBL23610369 | 0.87 | KDM4E (0.71) | KDM4EUSP2ALDH1A1HPGDALOX15 | |
| SCHEMBL17737082 | 0.87 | KDM4E (0.71) | KDM4EUSP2ALDH1A1HPGDALOX15 | |
| SCHEMBL2742813 | 0.86 | NPC1 (0.66) | KMOGSK3BKDM4EUSP2ALDH1A1 | |
| SCHEMBL3824666 | 0.86 | GSK3B (0.66) | KMOGSK3BKDM4EALDH1A1HPGD | |
| SCHEMBL1643417 | 0.85 | KMO (0.68) | KMOGSK3BKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 626 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-1188405-C | New Morpholinobenzamide salts | ASTRAZENECA AB (SE) | 2005-02-09 | — | — | CN | claimed |
| US-20050010045-A1 | Reacting morpholine compound with a substituted benzene compound | TIAN WEI (SE) | 2005-01-13 | — | — | US | claimed |
| US-6689882-B2 | REACTING A MORPHOLINE WITH A SUBSTITUTED BENZENE, WHEREIN MORPHOLINE IS USED AS A REACTANT AND AS THE ONLY ONE SOLVENT | ASTRAZENECA AB (SE) | 2004-02-10 | — | — | US | claimed |
| US-20030171581-A1 | Process for the synthesis of morpholinylbenzenes | ASTRAZENECA AB (SE) | 2003-09-11 | — | — | US | claimed |
| EP-1286977-A1 | A NEW PROCESS FOR THE SYNTHESIS OF MORPHOLINYLBENZENES | AstraZeneca AB (SE) | 2003-03-05 | — | — | EP | claimed |
| EP-0623635-B1 | Amine-functionalized polyester | GEN ELECTRIC (US) | 2003-02-19 | — | — | EP | claimed |
| CN-1337956-A | New Morpholinobenzamide salts | ASTRAZENECA AB (SE) | 2002-02-27 | — | — | CN | claimed |
| WO-2001087865-A1 | A NEW PROCESS FOR THE SYNTHESIS OF MORPHOLINYLBENZENES | ASTRAZENECA AB (SE) | 2001-11-22 | — | — | WO | claimed |
| EP-1149083-A1 | MORPHOLINOBENZAMIDE SALTS | AstraZeneca AB (SE) | 2001-10-31 | — | — | EP | claimed |
| US-6291458-B1 | Morpholinobenzamide salts | ASTRAZENECA AB (SE) | 2001-09-18 | — | — | US | claimed |
| WO-2000043378-A1 | NEW MORPHOLINOBENZAMIDE SALTS | ASTRAZENECA AB (SE) | 2000-07-27 | — | — | WO | claimed |
| JP-4247074-A | — | — | None | — | — | JP | disclosed |
| US-12522618-B2 | Copper complexes for treatment of neurodegenerative disorders | ALS THERAPY DEVELOPMENT INSTITUTE (US) | 2026-01-13 | — | — | US | disclosed |
| EP-4301736-B1 | MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2025-10-08 | — | — | EP | disclosed |
| WO-2025202864-A1 | ENT1 INHIBITORS IN COMBINATION WITH ONCOLYTIC VIRUSES AND THEIR USE IN THE TREATMENT OF CANCER | iTeos Belgium SA (BE) | 2025-10-02 | — | — | WO | disclosed |
| WO-1998048799-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |
| WO-1997034883-A1 | SUBSTITUTED 1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1997-09-25 | — | — | WO | disclosed |
| JP-H04247074-A | PRODUCTION OF 4-MORPHOLINOBENZOIC ACID DERIVATIVE | YOSHITOMI PHARMACEUT IND LTD | 1992-09-03 | — | — | JP | disclosed |
| US-4994569-A | Cholecystokinin antagonists | RHONE-POULENC SANTE (FR) | 1991-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171581-A1 | Process for the synthesis of morpholinylbenzenes | CYP1B1, TBCB, MAP1B | KMO 299/4885GSK3B 3101/4885KDM4E 2640/4885 |
| US-20050010045-A1 | Reacting morpholine compound with a substituted benzene compound | CYP1B1, MYB, MYBBP1A | KMO 237/4885GSK3B 4424/4885KDM4E 2799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.