Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4829187 | 0.86 | TSHR (0.42) | THRBTSHRALDH1A1HSD17B10 | |
| SCHEMBL6392986 | 0.83 | TSHR (0.53) | THRBTSHRALDH1A1 | |
| SCHEMBL9170709 | 0.81 | TSHR (0.34) | THRBTSHR | |
| SCHEMBL1275670 | 0.81 | CHRM1 (0.48) | THRBTSHRALDH1A1 | |
| SCHEMBL9171056 | 0.81 | THRB (0.32) | THRBTSHR | |
| SCHEMBL4829385 | 0.80 | — | — | |
| SCHEMBL57345 | 0.74 | THRB (0.50) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL1481676 | 0.74 | — | — | |
| SCHEMBL2768512 | 0.74 | — | — | |
| SCHEMBL7184471 | 0.72 | THRB (0.39) | THRBTSHRALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329763-B2 | Hydrogel | EVONIK ROEHM GMBH (DE) | 2012-12-11 | — | — | US | claimed |
| US-20120145942-A1 | Hydrogel | EVONIK ROEHM GMBH (DE) | 2012-06-14 | — | — | US | claimed |
| CN-100400561-C | Hydrogel | ROEHM GMBH (DE) | 2008-07-09 | — | — | CN | claimed |
| US-20060264571-A1 | Hydrogel | ROHM GMBH (DE) | 2006-11-23 | — | — | US | claimed |
| CN-1856517-A | Hydrogel | ROEHM GMBH (DE) | 2006-11-01 | — | — | CN | claimed |
| US-8329763-B2 | Hydrogel | EVONIK ROEHM GMBH (DE) | 2012-12-11 | — | — | US | disclosed |
| US-20120145942-A1 | Hydrogel | EVONIK ROEHM GMBH (DE) | 2012-06-14 | — | — | US | disclosed |
| CN-100400561-C | Hydrogel | ROEHM GMBH (DE) | 2008-07-09 | — | — | CN | disclosed |
| US-20060264571-A1 | Hydrogel | ROHM GMBH (DE) | 2006-11-23 | — | — | US | disclosed |
| CN-1856517-A | Hydrogel | ROEHM GMBH (DE) | 2006-11-01 | — | — | CN | disclosed |