Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6065052 | 0.81 | THRB (0.40) | TSHRTHRB | |
| SCHEMBL10628321 | 0.80 | TSHR (0.55) | TSHRALOX15THRBCHRNB2CHRNA4 | |
| SCHEMBL4829187 | 0.78 | TSHR (0.42) | TSHRTHRB | |
| SCHEMBL6392986 | 0.74 | TSHR (0.53) | TSHRTHRB | |
| SCHEMBL503551 | 0.74 | NAAA (0.47) | ALOX15CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL9171056 | 0.73 | THRB (0.32) | TSHRTHRB | |
| SCHEMBL1275670 | 0.73 | CHRM1 (0.48) | TSHRTHRBCHRNB2CHRNA4 | |
| SCHEMBL4829385 | 0.73 | — | — | |
| SCHEMBL29655367 | 0.73 | — | — | |
| SCHEMBL20446689 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424472-A | Method of manufacturing a (meth)acryloylthio compound | ROEHM GMBH CHEMISCHE FABRIK PATENTABTEILUNG (DE) | 1995-06-13 | — | — | US | disclosed |