Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6065295 | 0.90 | IDO1 (0.33) | MALT1BCHECKS1BSKP1SKP2 | |
| SCHEMBL6427256 | 0.90 | BCHE (0.35) | MALT1BCHECKS1BSKP1SKP2 | |
| SCHEMBL3112862 | 0.89 | MAPK1 (0.30) | — | |
| SCHEMBL28758008 | 0.83 | SCN9A (0.32) | SCN9A | |
| SCHEMBL6066213 | 0.81 | TDP1 (0.36) | ITGA4ITGB7MALT1IDO1MEN1 | |
| SCHEMBL27641140 | 0.81 | ACSS2 (0.32) | — | |
| SCHEMBL6065063 | 0.81 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL3114245 | 0.79 | SLC6A1 (0.33) | — | |
| SCHEMBL3121409 | 0.79 | CTSS (0.37) | CKS1BSKP1SKP2AKT1RORC | |
| SCHEMBL3123213 | 0.78 | NTRK1 (0.35) | MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1852715-A | Cephem compounds | ASTELLAS PHARMA INC (JP) | 2006-10-25 | — | — | CN | disclosed |
| EP-1663245-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005027909-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2005-03-31 | — | — | WO | disclosed |