Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | DHPS | P49366 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6399457 | 0.90 | SOAT1 (0.37) | THRBTHRASOAT1MAPTALDH1A1 | |
| SCHEMBL697379 | 0.74 | PDE5A (0.39) | THRBDHPSTHRASOAT1MEN1 | |
| SCHEMBL627672 | 0.72 | CYP1A2 (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2USP2 | |
| SCHEMBL27875103 | 0.70 | SOAT1 (0.50) | THRBTHRASOAT1MEN1KMT2A | |
| SCHEMBL31099296 | 0.70 | SOAT1 (0.45) | SOAT1MEN1KMT2APTPN11CYP3A4 | |
| SCHEMBL27615672 | 0.68 | SOAT1 (0.55) | THRBTHRASOAT1 | |
| SCHEMBL1372005 | 0.66 | LMNA (0.36) | THRBTHRAMAPTSMN1; SMN2PTPN11 | |
| SCHEMBL7213943 | 0.66 | PTPN11 (0.49) | PTPN11LMNA | |
| SCHEMBL27825581 | 0.66 | SOAT1 (0.40) | THRBTHRASOAT1 | |
| SCHEMBL4248262 | 0.65 | SOAT1 (0.40) | THRBTHRASOAT1ALDH1A1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1703892-A2 | UV LIGHT-STABLE SEMI-SOLID TRANSDERMAL SYSTEMS COMPRISING A PHOTOSENSITIVE ACTIVE AGENT AND AN UV-ABSORBING COMPONENT | Schering AG (DE) | 2006-09-27 | — | — | EP | disclosed |
| WO-2005055975-A2 | UV-STABLE SEMI-SOLID TRANSDERMAL SYSTEMS COMPRISING A PHOTOSENSITIVE ACTIVE INGREDIENT AND A UV ABSORBER | SCHERING AG (DE) | 2005-06-23 | — | — | WO | disclosed |