Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.36 |
| ▸ | RELA | Q04206 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1697181 | 0.83 | LMNA (0.37) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL627672 | 0.79 | CYP1A2 (0.39) | LMNASMN1; SMN2TP53TSHRCYP1A2 | |
| SCHEMBL3434962 | 0.76 | ELANE (0.33) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL148645 | 0.75 | NR5A1 (0.45) | TP53TSHRTHRATHRBPLA2G4B | |
| SCHEMBL29362798 | 0.75 | NR5A1 (0.45) | TP53TSHRTHRATHRBPLA2G4B | |
| SCHEMBL3134741 | 0.74 | SGMS2 (0.34) | LMNACYP3A4MAPT | |
| SCHEMBL6399457 | 0.74 | SOAT1 (0.37) | THRATHRBCYP1A2CYP2C19MAPT | |
| SCHEMBL28326279 | 0.73 | ESR1 (0.36) | NPC1TP53TSHRTHRATHRB | |
| SCHEMBL28598128 | 0.71 | TP53 (0.48) | TP53TSHRTHRATHRBPLA2G4B | |
| SCHEMBL27600953 | 0.71 | CYP1A2 (0.51) | LMNATHRATHRBCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2575750-A2 | SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE | International Flora Technologies, Ltd. (US) | 2013-04-10 | — | — | EP | claimed |
| WO-2011149929-A2 | SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE | INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) | 2011-12-01 | — | — | WO | claimed |
| US-20110286946-A1 | SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE | INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) | 2011-11-24 | — | — | US | claimed |
| CN-114983866-B | Reticular macromolecule sun-proof film cosmetic composition | 广州科创材料科技有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-110049754-B | Fatty acid ethyl ester for cosmetics | CJ第一制糖株式会社 | 2022-12-06 | — | — | CN | disclosed |
| US-10947347-B2 | Hyrophilic ethylene oxide free emulsifier comprising dendrimeric polyhydroxylated ester moieties | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2021-03-16 | — | — | US | disclosed |
| EP-3204455-B1 | HYDROPHILIC ETHYLENE OXIDE FREE EMULSIFIER COMPRISING DENDRIMERIC POLYHYDROXYLATED ESTER MOIETIES | MOMENTIVE PERFORMANCE MAT GMBH (DE) | 2020-04-29 | — | — | EP | disclosed |
| EP-2504381-B1 | HYDROPHILIC/LIPOPHILIC MODIFIED POLYSILOXANES AS EMULSIFIERS | MOMENTIVE PERFORMANCE MAT GMBH (DE) | 2018-03-07 | — | — | EP | disclosed |
| US-9751063-B2 | Emulsion compositions and applications therefor | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2017-09-05 | — | — | US | disclosed |
| EP-3204455-A1 | HYDROPHILIC ETHYLENE OXIDE FREE EMULSIFIER COMPRISING DENDRIMERIC POLYHYDROXYLATED ESTER MOIETIES | Momentive Performance Materials GmbH (DE) | 2017-08-16 | — | — | EP | disclosed |
| US-9340650-B2 | Hydrophilic/lipophilic modified polysiloxanes as emsulsifiers | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2016-05-17 | — | — | US | disclosed |
| WO-2016057317-A1 | HYDROPHILIC ETHYLENE OXIDE FREE EMULSIFIER COMPRISING DENDRIMERIC POLYHYDROXYLATED ESTER MOIETIES | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2016-04-14 | — | — | WO | disclosed |
| US-20160102179-A1 | HYROPHILIC ETHYLENE OXIDE FREE EMULSIFIER COMPRISING DENDRIMERIC POLYHYDROXYLATED ESTER MOIETIES | CITIBANK, N.A., AS ADMINISTRATIVE AGENT | 2016-04-14 | — | — | US | disclosed |
| US-20150157996-A1 | EMULSION COMPOSITIONS AND APPLICATIONS THEREFOR | MOMENTIVE PERFORMANCE MATERIALS INC. | 2015-06-11 | — | — | US | disclosed |
| US-20120289649-A1 | Hydrophilic/Lipophilic Modified Polysiloxanes As Emsulsifiers | Momentive-Performance Materials GmbH (DE) | 2012-11-15 | — | — | US | disclosed |
| EP-2504381-A1 | HYDROPHILIC/LIPOPHILIC MODIFIED POLYSILOXANES AS EMULSIFIERS | Momentive Performance Materials GmbH (DE) | 2012-10-03 | — | — | EP | disclosed |
| US-20110286946-A1 | SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE | INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) | 2011-11-24 | — | — | US | disclosed |
| WO-2011064255-A1 | HYDROPHILIC/LIPOPHILIC MODIFIED POLYSILOXANES AS EMULSIFIERS | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2011-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10947347-B2 | Hyrophilic ethylene oxide free emulsifier comprising dendrimeric polyhydroxylated ester moieties | HAO2, PAOX, ELOVL1 | LMNA 3065/4885NPC1 4400/4885NFKB1 2921/4885 |
| US-20120289649-A1 | Hydrophilic/Lipophilic Modified Polysiloxanes As Emsulsifiers | MGLL, ELOVL1, PLOD3 | LMNA 298/4885NPC1 1372/4885NFKB1 3298/4885 |
| US-20160102179-A1 | HYROPHILIC ETHYLENE OXIDE FREE EMULSIFIER COMPRISING DENDRIMERIC POLYHYDROXYLATED ESTER MOIETIES | HAO2, PAOX, ELOVL1 | LMNA 3065/4885NPC1 4400/4885NFKB1 2921/4885 |
| US-20150157996-A1 | EMULSION COMPOSITIONS AND APPLICATIONS THEREFOR | POLR1C, POLQ, POLH | LMNA 389/4885NPC1 3165/4885NFKB1 2242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.