Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13172008 | 0.83 | APP (0.63) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL701808 | 0.81 | HDAC3 (0.54) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL701807 | 0.81 | HDAC3 (0.54) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6064517 | 0.79 | ALDH1A1 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10625694 | 0.79 | RAB9A (0.53) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL5707178 | 0.79 | RAB9A (0.53) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL9486859 | 0.79 | RAB9A (0.53) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL24027069 | 0.79 | APP (0.51) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28367287 | 0.79 | APP (0.58) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21758695 | 0.78 | APP (0.50) | APPHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084281-B2 | Synthesis of dihalohydrins and tri- and tetra-substituted olefins | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-08-01 | — | — | US | disclosed |
| US-20040143125-A1 | Synthesis of dihalohydrins and tri- and tetra-substituted olefins | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040143125-A1 | Synthesis of dihalohydrins and tri- and tetra-substituted olefins | TALDO1, HDHD5, TKT | APP 4511/4885HDAC3 2151/4885HDAC4 2806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.