Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 14/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5954788 | 0.94 | TYMP (0.61) | TYMPADORA1P2RY6 | |
| SCHEMBL7651830 | 0.84 | TYMP (0.60) | TYMPADORA1 | |
| SCHEMBL261566 | 0.83 | TYMP (0.50) | TYMPADORA1P2RY6 | |
| SCHEMBL7261556 | 0.83 | TYMP (0.50) | TYMPADORA1P2RY6 | |
| SCHEMBL5038377 | 0.83 | ALDH1A1 (0.62) | P2RY6 | |
| SCHEMBL11430667 | 0.83 | LMNA (0.64) | TYMP | |
| SCHEMBL11796922 | 0.83 | LMNA (0.64) | TYMP | |
| SCHEMBL234387 | 0.82 | LMNA (0.46) | P2RY6 | |
| SCHEMBL1684799 | 0.82 | ADK (0.52) | P2RY6 | |
| SCHEMBL21998920 | 0.82 | ADK (0.52) | P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648910-A2 | ANTISENSE MODULATION OF STEAROYL-COA DESATURASE EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005014607-A2 | ANTISENSE MODULATION OF STEAROYL-COA DESATURASE EXPRESSION | ISIS PHARMACEUTICALS INC. (US) | 2005-02-17 | — | — | WO | disclosed |