SCHEMBL6065673

SCHEMBL6065673

CC(=O)O[C@H]1[C@H](n2cc(C)c(=O)[nH]c2=S)O[C@@](COCc2ccccc2)(COS(C)(=O)=O)[C@H]1OCc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TK1 P04183 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14511225 1.00 TK1 (0.34) TK1
SCHEMBL20394057 0.92 TK1 (0.37) TK1
SCHEMBL20394055 0.92 TK1 (0.37) TK1
SCHEMBL28749276 0.92 TK1 (0.37) TK1
SCHEMBL28618584 0.89 TK1 (0.39) TK1
SCHEMBL28618582 0.89 TK1 (0.39) TK1
SCHEMBL5696121 0.89 TK1 (0.39) TK1
SCHEMBL9961264 0.86 TK1 (0.37) TK1
SCHEMBL14536634 0.84 TK2 (0.32)
SCHEMBL1097256 0.83 TK1 (0.39) TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9464106-B2 Oligonucleotides useful for detecting and analyzing nucleic acids of interest EXIQON A/S (DK) 2016-10-11 US disclosed
US-20120157333-A1 OLIGONUCLEOTIDES USEFUL FOR DETECTING AND ANALYZING NUCLEIC ACIDS OF INTEREST EXIQON A/S (DK) 2012-06-21 US disclosed
US-20060147924-A1 Population of nucleic acids including a subpopulation of lna oligomers EXIQON A/S (DK) 2006-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060147924-A1 Population of nucleic acids including a subpopulation of lna oligomers NSUN2, NCL, RNGTT TK1 62/4885
US-20120157333-A1 OLIGONUCLEOTIDES USEFUL FOR DETECTING AND ANALYZING NUCLEIC ACIDS OF INTEREST UPF1, DCLRE1B, SNRPA1 TK1 660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.