SCHEMBL6067477

SCHEMBL6067477

C=C(C)C(=O)NC[Si](C)(OCC)OCC

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
ALDH1A1 P00352 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
TGFBR1 P36897 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6066783 0.85 THRB (0.35) THRBALDH1A1MGAMGAASI
SCHEMBL6067457 0.83 THRB (0.36) THRBALDH1A1MGAMGAASI
SCHEMBL6066883 0.81 ALDH1A1 (0.38) ALDH1A1TGFBR1
SCHEMBL11128147 0.81 ACHE (0.33) THRB
SCHEMBL25388302 0.80 KDM4E (0.34) THRB
SCHEMBL25388563 0.78 KDM4E (0.37)
SCHEMBL25386373 0.78 KDM4E (0.37)
SCHEMBL2461687 0.75 ALOX15 (0.34) ALDH1A1MGAMGAASIMGAM2
SCHEMBL477439 0.75 EPHX1 (0.39) MGAMGAASIMGAM2
SCHEMBL29440665 0.74 THRB (0.35) THRBALDH1A1MGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179251-A1 COMPOSITION COMPRISING METHACRYLAMIDE GROUP-CONTAINING ORGANIC SILICON COMPOUND AND ARTICLE SURFACE-TREATED WITH SAID COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-06-05 US disclosed
WO-2006087079-A1 COMPOSITIONS CURED BY MICHAEL ADDITION REACTION Consortium für elektrochemische Industrie GmbH (DE) 2006-08-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179251-A1 COMPOSITION COMPRISING METHACRYLAMIDE GROUP-CONTAINING ORGANIC SILICON COMPOUND AND ARTICLE SURFACE-TREATED WITH SAID COMPOSITION CHRM1, CHRM2, CD68 THRB 1858/4885ALDH1A1 2154/4885MGAM 1411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.