Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 7/20 | 0.42 |
| ▸ | CD14 | P08571 | 7/20 | 0.42 |
| ▸ | LY96 | Q9Y6Y9 | 7/20 | 0.42 |
| ▸ | THRA | P10827 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 4/20 | 0.41 |
| ▸ | GSTA1 | P08263 | 3/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16440318 | 0.78 | THRA (0.42) | THRATHRB | |
| SCHEMBL6067644 | 0.78 | TLR4 (0.43) | TLR4CD14LY96THRATHRB | |
| SCHEMBL14353074 | 0.78 | TLR4 (0.43) | TLR4CD14LY96THRATHRB | |
| SCHEMBL6395446 | 0.75 | MAPT (0.39) | HTR2A | |
| SCHEMBL6067581 | 0.74 | GSTA1 (0.43) | TLR4CD14LY96THRATHRB | |
| SCHEMBL13309593 | 0.73 | LTA4H (0.42) | TSHRNPC1RAB9A | |
| SCHEMBL16440321 | 0.73 | PLA2G2A (0.44) | TSHRNPC1RAB9A | |
| SCHEMBL30702676 | 0.73 | GSTA1 (0.57) | TLR4CD14LY96GSTA1GSTP1 | |
| SCHEMBL6067606 | 0.73 | GSTA1 (0.57) | TLR4CD14LY96GSTA1GSTP1 | |
| SCHEMBL14353332 | 0.72 | GSTA1 (0.47) | TLR4CD14LY96THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006056182-A1 | NOVEL ACTIVE SUBSTANCES FOR TREATING, DIAGNOSING AND PREVENTING MACULAR DEGENERATION | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2006-06-01 | — | — | WO | disclosed |