Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 5/20 | 0.44 |
| ▸ | CCND1 | P24385 | 5/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.44 |
| ▸ | GSK3B | P49841 | 3/20 | 0.44 |
| ▸ | GSK3A | P49840 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | PRKCB | P05771 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | PRKACG | P22612 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5387156 | 0.79 | CDK4 (0.49) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL549156 | 0.79 | CDK4 (0.57) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL11903054 | 0.72 | CDK4 (0.55) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL29436003 | 0.72 | GPR3 (0.43) | MAPTALDH1A1KDM4ECASP3DDAH1 | |
| SCHEMBL110286 | 0.72 | GPR3 (0.43) | MAPTALDH1A1KDM4ECASP3DDAH1 | |
| SCHEMBL6995596 | 0.70 | MAPT (0.49) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL7902933 | 0.68 | CDK5 (0.47) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL3672266 | 0.68 | CDK4 (0.47) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL5766206 | 0.67 | CDK4 (0.42) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL5334328 | 0.64 | CDK4 (0.44) | CDK4CCND1CDK5CDK5R1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006068627-A1 | USE OF CONDENSATION PRODUCTS OF FATTY ACIDS, ALCOHOLS, PHENOLS, ALKYL PHENOLS AND AMINES WITH ETHYLENE OXIDE AND/OR PROPYLENE OXIDE AS AN ESSENTIAL OR SOLE COMPONENT OF AN ADDITIVE | VUCHT, A.S. (SK) | 2006-06-29 | — | — | WO | claimed |