Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29085030 | 0.89 | ESR1 (0.77) | ESR1ESR2HSD17B10MAOAUGT1A1 | |
| SCHEMBL5704963 | 0.81 | CA1 (0.47) | ESR1ESR2HSD17B10 | |
| SCHEMBL6068334 | 0.77 | ESR1 (0.47) | ESR1ESR2TYRALOX5 | |
| SCHEMBL6067884 | 0.77 | ESR1 (0.47) | ESR1ESR2HSD17B10 | |
| SCHEMBL6067913 | 0.74 | ESR1 (0.53) | ESR1ESR2HSD17B10TYRALOX5 | |
| SCHEMBL6067912 | 0.74 | ESR1 (0.53) | ESR1ESR2HSD17B10TYRALOX5 | |
| SCHEMBL29085004 | 0.73 | ESR1 (0.70) | ESR1ESR2HSD17B10 | |
| SCHEMBL6137031 | 0.73 | CA1 (0.50) | ESR1ESR2HSD17B10 | |
| SCHEMBL6067868 | 0.72 | ESR1 (0.46) | ESR1ESR2HSD17B10 | |
| SCHEMBL9773297 | 0.71 | RAB9A (0.47) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100349886-C | 1, 3-dihydroxybenzene derivatives and coloring agents containing the same | WELLA AG (US) | 2007-11-21 | — | — | CN | disclosed |
| US-7125428-B2 | 1,3-Dihydroxybenzene derivatives and colorants containing said compounds | WELLA AG (DE) | 2006-10-24 | — | — | US | disclosed |
| CN-1633426-A | 1, 3-dihydroxybenzene derivatives and coloring agents containing the same | WELLA AG (US) | 2005-06-29 | — | — | CN | disclosed |
| EP-1392673-B1 | 1,3-DIHYDROXYBENZENE DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2005-06-08 | — | — | EP | disclosed |
| US-20040016063-A1 | 1,3-Dihydroxybenzene derivatives and colorants containing said compounds | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2004-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040016063-A1 | 1,3-Dihydroxybenzene derivatives and colorants containing said compounds | KRT18, DSP, COL1A1 | ESR1 2061/4885ESR2 1641/4885HSD17B10 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.