Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705018 | 0.85 | CASP1 (0.41) | ESR1ESR2TYRMAPTTDP1 | |
| SCHEMBL6067884 | 0.77 | ESR1 (0.47) | ESR1ESR2MAPTMEN1POLB | |
| SCHEMBL6068029 | 0.77 | ESR1 (0.61) | ESR1ESR2TYRALOX5 | |
| SCHEMBL6067983 | 0.72 | ABL1 (0.38) | ESR1ESR2MAPTTDP1KDM4E | |
| SCHEMBL6872296 | 0.72 | CASP1 (0.37) | ESR1ESR2MAPTTDP1KDM4E | |
| SCHEMBL4948367 | 0.72 | ESR2 (0.43) | ESR1ESR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL3715393 | 0.71 | CES1 (0.39) | MAPTMEN1MAPK1KMT2AALDH1A1 | |
| SCHEMBL6067991 | 0.70 | ESR1 (0.42) | ESR1ESR2ALOX5MAPTNPSR1 | |
| SCHEMBL29623114 | 0.68 | ALOX5 (0.62) | ESR1ESR2TYRALOX5MAPT | |
| SCHEMBL278749 | 0.68 | ALOX5 (0.62) | ESR1ESR2TYRALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100349886-C | 1, 3-dihydroxybenzene derivatives and coloring agents containing the same | WELLA AG (US) | 2007-11-21 | — | — | CN | disclosed |
| US-7125428-B2 | 1,3-Dihydroxybenzene derivatives and colorants containing said compounds | WELLA AG (DE) | 2006-10-24 | — | — | US | disclosed |
| CN-1633426-A | 1, 3-dihydroxybenzene derivatives and coloring agents containing the same | WELLA AG (US) | 2005-06-29 | — | — | CN | disclosed |
| US-20040016063-A1 | 1,3-Dihydroxybenzene derivatives and colorants containing said compounds | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2004-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040016063-A1 | 1,3-Dihydroxybenzene derivatives and colorants containing said compounds | KRT18, DSP, COL1A1 | ESR1 2061/4885ESR2 1641/4885TYR 219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.