Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.62 |
| ▸ | BCR | P11274 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.62 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1027189 | 0.90 | HDAC4 (0.62) | ABL1ABCB1BCRCYP1A1CYP1A2 | |
| SCHEMBL196765 | 0.85 | CYP3A4 (0.73) | ABL1ABCB1BCRCYP1A1CYP1A2 | |
| SCHEMBL29489425 | 0.85 | CYP3A4 (0.73) | ABL1ABCB1BCRCYP1A1CYP1A2 | |
| SCHEMBL24177866 | 0.84 | ABL1 (0.79) | ABL1ABCB1BCRCYP1A1CYP1A2 | |
| SCHEMBL21296972 | 0.84 | ABL1 (0.73) | ABL1ABCB1BCRNPC1TP53 | |
| SCHEMBL1513611 | 0.84 | ABL1 (0.79) | ABL1ABCB1BCRCYP1A1CYP1A2 | |
| SCHEMBL5620245 | 0.83 | CYP3A4 (0.86) | ABL1ABCB1BCRCYP1A1CYP1A2 | |
| SCHEMBL29628977 | 0.83 | CYP3A4 (0.77) | ABL1ABCB1BCRCYP1A1CYP1A2 | |
| Hydrogen Sulfide SCHEMBL28640169 | 0.83 | CYP3A4 (0.70) | ABL1ABCB1BCRCYP1A1CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL27960505 | 0.83 | CYP3A4 (0.70) | ABL1ABCB1BCRCYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125428-B2 | 1,3-Dihydroxybenzene derivatives and colorants containing said compounds | WELLA AG (DE) | 2006-10-24 | — | — | US | disclosed |
| EP-1392673-A2 | 1,3-DIHYDROXYBENZENE DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-20040016063-A1 | 1,3-Dihydroxybenzene derivatives and colorants containing said compounds | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2004-01-29 | — | — | US | disclosed |
| WO-2002096901-A2 | 1,3-DIHYDROXYBENZENE DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040016063-A1 | 1,3-Dihydroxybenzene derivatives and colorants containing said compounds | KRT18, DSP, COL1A1 | ABL1 2506/4885ABCB1 860/4885BCR 1896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.