SCHEMBL6068094

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5704940	0.80	TAAR1 (0.52)	ALOX5ESR1HPGDMEN1KMT2A
	SCHEMBL12700773	0.80	CASP6 (0.53)	ESR1ESR2HPGDMEN1KMT2A
	SCHEMBL32665680	0.78	MEN1 (0.56)	HPGDMEN1KMT2AKDM4ECYP2C9
	SCHEMBL8658064	0.78	MEN1 (0.56)	HPGDMEN1KMT2AKDM4ECYP2C9
	SCHEMBL13343650	0.78	ESR1 (0.39)	ESR1ESR2HPGDMEN1KMT2A
	SCHEMBL3570032	0.78	TAAR1 (0.42)	ESR1ESR2CYP3A4CYP2C9CYP2C19
	SCHEMBL3567606	0.78	ESR1 (0.51)	ESR1ESR2HPGDMEN1KMT2A
	SCHEMBL3574793	0.76	ADORA2A (0.44)	ESR1HPGDMEN1KMT2AKDM4E
	SCHEMBL19568028	0.76	TRPA1 (0.50)	HPGDMEN1KMT2AKDM4EGAA
	SCHEMBL3570926	0.76	TAAR1 (0.56)	HPGDMEN1KMT2AKDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.