Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.37 |
| ▸ | CASP1 | P29466 | 8/20 | 0.37 |
| ▸ | CASP7 | P55210 | 8/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.32 |
| ▸ | USP2 | O75604 | 4/20 | 0.31 |
| ▸ | GLA | P06280 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068853 | 0.73 | ELOVL1 (0.39) | CYP3A4CYP2C9MEN1CYP2C19KMT2A | |
| SCHEMBL33797 | 0.70 | ALDH1A1 (0.37) | ALDH1A1HPGDGLATSHRLMNA | |
| SCHEMBL5021082 | 0.69 | LRRK2 (0.40) | ALDH1A1CYP1A2HSD17B10HPGDCYP3A4 | |
| Hydrochloric Acid SCHEMBL5414502 | 0.69 | ALDH1A1 (0.36) | ALDH1A1HPGDGLATSHRLMNA | |
| Hydrochloric Acid SCHEMBL6282164 | 0.69 | ALDH1A1 (0.36) | ALDH1A1HPGDGLATSHRLMNA | |
| SCHEMBL6068941 | 0.68 | CA2 (0.31) | ALDH1A1 | |
| SCHEMBL6068710 | 0.68 | HRH4 (0.36) | ALDH1A1HPGDPIM1 | |
| SCHEMBL6068715 | 0.68 | CNR2 (0.38) | ALDH1A1HSD17B10HPGDUSP2 | |
| SCHEMBL15882053 | 0.67 | MAOB (0.36) | ALDH1A1TSHRLMNAALOX15 | |
| SCHEMBL17076898 | 0.67 | ALDH1A1 (0.39) | ALDH1A1HPGDGLATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091350-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2006-08-15 | — | — | US | disclosed |
| US-20040088802-A1 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL S.A. (FR) | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040088802-A1 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | CBR3, CBR1, CYB5R3 | ALDH1A1 1944/4885CYP1A2 957/4885CASP1 2497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.