Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2923501 | 0.75 | MEN1 (0.37) | ALDH1A1MAPT | |
| SCHEMBL1076637 | 0.72 | ALDH1A1 (0.37) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14401659 | 0.69 | HTT (0.37) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1074374 | 0.69 | PKM (0.40) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6068366 | 0.67 | SMPD3 (0.39) | — | |
| SCHEMBL8920797 | 0.66 | ALDH1A1 (0.36) | ALDH1A1MAPTSMN1; SMN2 | |
| Bromide SCHEMBL6068862 | 0.66 | SMPD3 (0.38) | — | |
| Bromide SCHEMBL6068466 | 0.66 | SMPD3 (0.38) | — | |
| SCHEMBL2929425 | 0.66 | MAPT (0.32) | ALDH1A1MAPT | |
| SCHEMBL8920031 | 0.65 | ALDH1A1 (0.36) | ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091350-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2006-08-15 | — | — | US | disclosed |
| US-20040088802-A1 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL S.A. (FR) | 2004-05-13 | — | — | US | disclosed |
| EP-1363889-A1 | NOVEL DIAMINOPYRAZOLE DERIVATIVES AND THEIR USE FOR OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002066440-A1 | DIAMINOPYRAZOLE DERIVATIVES AND THEIR USE FOR OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040088802-A1 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | CBR3, CBR1, CYB5R3 | ALDH1A1 1944/4885MAPT 1800/4885RECQL 1024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.