Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557221 | 0.83 | HDAC1 (0.56) | KDM4EHDAC1HDAC8HDAC6L3MBTL1 | |
| SCHEMBL6069372 | 0.83 | CYP1A2 (0.50) | ALDH1A1KMT2AKDM4EMAPTHDAC1 | |
| SCHEMBL6259279 | 0.77 | TNIK (0.49) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL6069201 | 0.77 | HDAC8 (0.48) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| Hydrochloric Acid SCHEMBL2990577 | 0.76 | TNIK (0.48) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL6069465 | 0.75 | CA12 (0.57) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL7563743 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL6069135 | 0.74 | MAPT (0.41) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL22288489 | 0.73 | SHMT2 (0.50) | ALDH1A1KMT2AMEN1MAPTALOX15 | |
| SCHEMBL31577324 | 0.73 | SHMT2 (0.50) | ALDH1A1KMT2AMEN1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074243-B2 | N-benzyl-m-phenylenediamine derivatives and dyes containing said compounds | WELLA AG (DE) | 2006-07-11 | — | — | US | claimed |
| CN-1529691-A | N-benzyl-m-phenylenediamine derivatives and colorants containing these compounds | P&G | 2004-09-15 | — | — | CN | claimed |
| EP-1390341-A1 | N-BENZYL-M-PHENYLENEDIAMINE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2004-02-25 | — | — | EP | claimed |
| US-20030182735-A1 | N-benzyl-m-phenylenediamine derivatives and dyes containing said compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | US | claimed |
| WO-2002096854-A1 | N-BENZYL-M-PHENYLENEDIAMINE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-05 | — | — | WO | claimed |
| US-7074243-B2 | N-benzyl-m-phenylenediamine derivatives and dyes containing said compounds | WELLA AG (DE) | 2006-07-11 | — | — | US | disclosed |
| EP-1390341-A1 | N-BENZYL-M-PHENYLENEDIAMINE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-20030182735-A1 | N-benzyl-m-phenylenediamine derivatives and dyes containing said compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | US | disclosed |
| WO-2002096854-A1 | N-BENZYL-M-PHENYLENEDIAMINE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030182735-A1 | N-benzyl-m-phenylenediamine derivatives and dyes containing said compounds | KRT18, VIM, KPNB1 | ALDH1A1 601/4885KMT2A 2274/4885KDM4E 1903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.