Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MC4R | P32245 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | TACR3 | P29371 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6069703 | 1.00 | KMT2A (0.57) | KMT2AALDH1A1MEN1MC4RMAPT | |
| SCHEMBL6070046 | 0.90 | KMT2A (0.60) | KMT2AALDH1A1MEN1MC4RLMNA | |
| SCHEMBL6070052 | 0.90 | KMT2A (0.60) | KMT2AALDH1A1MEN1MC4RLMNA | |
| SCHEMBL6708055 | 0.90 | KMT2A (0.69) | KMT2AALDH1A1MEN1MC4RLMNA | |
| SCHEMBL6708057 | 0.90 | KMT2A (0.69) | KMT2AALDH1A1MEN1MC4RLMNA | |
| SCHEMBL6069745 | 0.84 | KMT2A (0.52) | KMT2AALDH1A1MEN1MC4RLMNA | |
| SCHEMBL6069737 | 0.84 | KMT2A (0.52) | KMT2AALDH1A1MEN1MC4RLMNA | |
| SCHEMBL7598387 | 0.82 | CHRM1 (0.52) | KMT2ACYP3A4SCN9A | |
| SCHEMBL6161351 | 0.82 | KMT2A (0.57) | KMT2AALDH1A1LMNACYP3A4SCN9A | |
| SCHEMBL6069919 | 0.81 | LMNA (0.54) | KMT2AALDH1A1MEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067518-B2 | Pyridinyl-methyl-ethyl cyclohexanecarboxamides as serotonergic agents | WYETH (US) | 2006-06-27 | — | — | US | disclosed |
| US-20050107395-A1 | Pyridinyl-methyl-ethyl cyclohexanecarboxamides as serotonergic agents | WYETH | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107395-A1 | Pyridinyl-methyl-ethyl cyclohexanecarboxamides as serotonergic agents | HTR1A, HTR5A, HTR2C | KMT2A 742/4885ALDH1A1 1298/4885MEN1 1771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.