Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL9230061 | 0.88 | ALDH1A1 (0.46) | CYP3A4ALDH1A1ALOX15HIF1ATSHR | |
| Acetonitrile SCHEMBL7460309 | 0.88 | ALDH1A1 (0.40) | CYP3A4ALDH1A1TSHR | |
| Acetonitrile SCHEMBL21768801 | 0.88 | — | — | |
| Acetonitrile SCHEMBL156477 | 0.88 | — | — | |
| Acetonitrile SCHEMBL7647027 | 0.88 | ALDH1A1 (0.40) | CYP3A4ALDH1A1TSHR | |
| Chloroform SCHEMBL613360 | 0.88 | — | — | |
| Acetonitrile SCHEMBL2570656 | 0.88 | — | — | |
| Chloroform SCHEMBL7827442 | 0.88 | ALDH1A1 (0.46) | CYP3A4ALDH1A1ALOX15HIF1ATSHR | |
| Chloroform SCHEMBL181824 | 0.88 | — | — | |
| Chloroform SCHEMBL9236775 | 0.88 | ALDH1A1 (0.46) | CYP3A4ALDH1A1ALOX15HIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067667-B2 | Aminoalkyl-3, 4-dihydroquinoline derivatives as no-synthase inhibitors | SCHERING AKTIENGESELLSCHAFT (DE) | 2006-06-27 | — | — | US | disclosed |
| US-20040127712-A1 | Aminoalkyl-3, 4-dihydroquinoline derivatives as no-synthase inhibitors | JAROCH STEFAN (DE) | 2004-07-01 | — | — | US | disclosed |
| CN-1137097-C | Aminoalkyl-3, 4-dihydroquinoline derivatives as NO synthase inhibitors | ���ֹɷݹ�˾ | 2004-02-04 | — | — | CN | disclosed |
| CN-1319093-A | Aminoalkyl-3,4-dihydroquindine derivates as No-synthase inhibitors | SCHERING AG (DE) | 2001-10-24 | — | — | CN | disclosed |
| US-4894458-A | BACTERICIDES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127712-A1 | Aminoalkyl-3, 4-dihydroquinoline derivatives as no-synthase inhibitors | NOS3, NOS1, NOS2 | CYP3A4 36/4885ALDH1A1 260/4885ALOX15 1222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.