Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6069255 | 0.99 | SIGMAR1 (0.52) | SIGMAR1MCHR1BCHECNR1CNR2 | |
| SCHEMBL27227901 | 0.89 | ADORA2A (0.44) | SIGMAR1CNR1CNR2 | |
| SCHEMBL23412841 | 0.80 | HTR2A (0.44) | — | |
| SCHEMBL29780607 | 0.80 | HTR2A (0.44) | — | |
| SCHEMBL14636500 | 0.79 | SIGMAR1 (0.53) | SIGMAR1 | |
| SCHEMBL6118555 | 0.78 | SLC9A1 (0.40) | CNR1CNR2 | |
| SCHEMBL6069287 | 0.78 | MCHR1 (0.44) | SIGMAR1MCHR1BCHECNR1CNR2 | |
| SCHEMBL6069740 | 0.77 | ALDH1A1 (0.44) | SIGMAR1MCHR1BCHECNR1CNR2 | |
| SCHEMBL31429180 | 0.75 | P2RX7 (0.56) | MCHR1 | |
| SCHEMBL6069743 | 0.75 | MCHR1 (0.66) | SIGMAR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101948433-B | Method for separating and purifying substituted indazole isomer | UNIV ZHENGZHOU | 2012-05-09 | — | — | CN | claimed |
| CN-101948433-A | Method for separating and purifying substituted indazole isomers | UNIV ZHENGZHOU | 2011-01-19 | — | — | CN | claimed |
| CN-101948433-B | Method for separating and purifying substituted indazole isomer | UNIV ZHENGZHOU | 2012-05-09 | — | — | CN | disclosed |
| CN-101948433-A | Method for separating and purifying substituted indazole isomers | UNIV ZHENGZHOU | 2011-01-19 | — | — | CN | disclosed |
| US-7071182-B2 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABBOTT LABORATORIES (US) | 2006-07-04 | — | — | US | disclosed |
| US-20050277638-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABBVIE INC. | 2005-12-15 | — | — | US | disclosed |
| US-20050137243-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABBOTT LABORATORIES | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137243-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | SIGMAR1 242/4885MCHR1 1/4885BCHE 1148/4885 |
| US-20050277638-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | SIGMAR1 242/4885MCHR1 1/4885BCHE 1148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.